Zhang BY, Liang MW, Zhang SX. Type one autoimmune pancreatitis based on clinical diagnosis: A case report. World J Clin Cases 2024; 12(14): 2438-2444 [PMID: 38765756 DOI: 10.12998/wjcc.v12.i14.2438]
Corresponding Author of This Article
Bi-Yu Zhang, MS, Master's Student, Department of Gastroenterology, Guangzhou University of Chinese Medicine Shunde Hospital, No. 12 Jinsha Avenue, Daliang Street, Shunde District, Foshan 528300, Guangdong Province, China. 13824562729@163.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 16, 2024; 12(14): 2438-2444 Published online May 16, 2024. doi: 10.12998/wjcc.v12.i14.2438
Type one autoimmune pancreatitis based on clinical diagnosis: A case report
Bi-Yu Zhang, Mou-Wang Liang, Shuang-Xi Zhang
Bi-Yu Zhang, Mou-Wang Liang, Shuang-Xi Zhang, Department of Gastroenterology, Guangzhou University of Chinese Medicine Shunde Hospital, Foshan 528300, Guangdong Province, China
Bi-Yu Zhang, Department of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, China
Co-first authors: Bi-Yu Zhang and Mou-Wang Liang.
Author contributions: Zhang BY and Liang MW contributed equally to the article; Zhang BY and Liang MW contributed to data collection, data analysis and revised the content of the article; Zhang BY, Liang MW and Zhang SX wrote the paper; Zhang SX revised the article. All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist(2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bi-Yu Zhang, MS, Master's Student, Department of Gastroenterology, Guangzhou University of Chinese Medicine Shunde Hospital, No. 12 Jinsha Avenue, Daliang Street, Shunde District, Foshan 528300, Guangdong Province, China. 13824562729@163.com
Received: February 3, 2024 Revised: March 13, 2024 Accepted: April 3, 2024 Published online: May 16, 2024 Processing time: 94 Days and 17.3 Hours
Abstract
BACKGROUND
Autoimmune pancreatitis (AIP) is a rare form of autoimmune-mediated pancreatitis, which is easily misdiagnosed as pancreatic cancer and thus treated surgically. We studied the diagnosis and treatment of a patient with type 1 AIP recently admitted to our hospital, and reviewed the literature to provide a reference for clinical diagnosis of AIP.
CASE SUMMARY
The chief complaint was yellowing of the body, eyes and urine for 21 d. The patient's clinical presentation was obstructive jaundice and imaging suggested pancreatic swelling. It was difficult to distinguish between inflammation and tumor. Serum immunoglobulin G4 (IgG4) was markedly elevated. IgG4 is an important serological marker for type 1 AIP. The patient was diagnosed with AIP, IgG4-related cholangitis, acute cholecystitis and hepatic impairment. After applying hormonal therapy, the patient's symptoms improved significantly. At the same time, imaging suggested that pancreatic swelling subsided, and liver function and other biochemical indicators decreased. The treatment was effective.
CONCLUSION
In patients with pancreatic swelling, the possibility of AIP should be considered.
Core Tip: Autoimmune pancreatitis (AIP) has a low global incidence. Patients with pancreatic swelling need to differentiate between general pancreatitis and AIP. We report a clinical case and review the diagnosis of AIP in terms of clinical symptoms, physical examinations, laboratory examinations, and imaging examinations. To improve clinicians' ability to diagnose AIP will reduce misdiagnosis and increase the effectiveness of treatment.
