Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2024; 12(1): 130-135
Published online Jan 6, 2024. doi: 10.12998/wjcc.v12.i1.130
Erythrodermic mycosis fungoides: A case report
Wu-Bing Xu, Ya-Ping Zhang, Su-Ping Zhou, Hao-Yang Bai
Wu-Bing Xu, Ya-Ping Zhang, Su-Ping Zhou, Hao-Yang Bai, Department of Radiology, Shaoxing People’s Hospital, Key Laboratory of Functional Molecular Imaging of Tumor and Interventional Diagnosis and Treatment of Shaoxing City, Shaoxing 312000, Zhejiang Province, China
Author contributions: Bai HY and Zhou SP contributed equally to this work; Bai HY and Zhou SP were responsible for data searching; Xu WB wrote the paper; Zhang YP was responsible for writing instructions and communication contacts; and all authors have read and approved the final manuscript.
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Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
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Corresponding author: Ya-Ping Zhang, MBBS, Professor, Department of Radiology, Shaoxing People’s Hospital, Key Laboratory of Functional Molecular Imaging of Tumor and Interventional Diagnosis and Treatment of Shaoxing City, No. 568 North Zhongxing Road, Yuecheng District, Shaoxing 312000, Zhejiang Province, China. 281891582@qq.com
Received: September 19, 2023
Peer-review started: September 19, 2023
First decision: December 5, 2023
Revised: December 11, 2023
Accepted: December 19, 2023
Article in press: December 19, 2023
Published online: January 6, 2024
Processing time: 104 Days and 21.7 Hours
Abstract
BACKGROUND

Mycosis fungoides is the most common primary cutaneous T-cell lymphoma, whereas generalized erythroderma is rare. In this report, we describe a case of mycosis fungoides with generalized erythroderma using complete clinical data and [18F]fluoroDglucose positron emission tomography/computed tomography (18F-FDG PET/CT) images.

CASE SUMMARY

Systemic skin redness with desquamation for three years confirmed mycosis fungoides within one month. The patient underwent left axillary lymphadenectomy biopsy; pathological biopsy suggested abnormal T-cell lesions consistent with mycosis fungoides involving lymph nodes. The patient received methotrexate, 5 mg twice weekly, as part of their chemotherapy regimen. Patients January half after discharge, no obvious cause of high fever, left axillary lymph nodes with red heat pain, and rupture entered our hospital for treatment.

CONCLUSION

The 18F-FDG PET/CT is essential for early diagnosis and timely treatment.

Keywords: Mycosis fungoides; Positron emission tomography/computed tomography; Imaging; Diagnosis; Differential diagnosis; Treatment; Case report

Core Tip: Mycosis fungoides is the most common primary cutaneous T-cell lymphoma, whereas generalized erythroderma is rare. Patients with mycosis fungoides with erythroderma lesions are more severe and require poor treatment. The [18F]fluoroDglucose positron emission tomography/computed tomography is essential for early diagnosis and timely treatment. Understanding the clinical and radiographic features of this rare disease will facilitate a better therapeutic diagnosis in clinical practice.