Soh HY, Zhang WB, Yu Y, Zhang R, Chen Y, Gao Y, Peng X. Sclerosing odontogenic carcinoma of maxilla: A case report. World J Clin Cases 2023; 11(8): 1878-1887 [PMID: 36970007 DOI: 10.12998/wjcc.v11.i8.1878]
Corresponding Author of This Article
Xin Peng, DDS, MD, Professor, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No. 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, China. pxpengxin@263.net
Research Domain of This Article
Dentistry, Oral Surgery & Medicine
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 16, 2023; 11(8): 1878-1887 Published online Mar 16, 2023. doi: 10.12998/wjcc.v11.i8.1878
Sclerosing odontogenic carcinoma of maxilla: A case report
Hui Yuh Soh, Wen-Bo Zhang, Yao Yu, Ran Zhang, Yan Chen, Yan Gao, Xin Peng
Hui Yuh Soh, Wen-Bo Zhang, Yao Yu, Xin Peng, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China
Hui Yuh Soh, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia
Ran Zhang, Yan Chen, Yan Gao, Department of Oral Pathology, Peking University School of Stomatology, Beijing 100081, China
Author contributions: All authors have made substantial contributions to the manuscript; Soh HY, Zhang WB and Yu Y collected patient’s data, managed the patient, and drafted the manuscript; Zhang R and Chen Y prepared and performed microscopic examination of all the histology slides and drafted the manuscript; Chen Y and Gao Y helped interpret the histology slides and guided the diagnostic process; Peng X performed the surgery and revised the manuscript critically; All authors have read and approved the final version of the manuscript.
Informed consent statement: Written consent for publication was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xin Peng, DDS, MD, Professor, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, No. 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, China. pxpengxin@263.net
Received: January 8, 2023 Peer-review started: January 8, 2023 First decision: January 30, 2023 Revised: February 6, 2023 Accepted: February 22, 2023 Article in press: February 22, 2023 Published online: March 16, 2023 Processing time: 58 Days and 2 Hours
Abstract
BACKGROUND
Sclerosing odontogenic carcinoma is a rare primary intraosseous neoplasm that was featured recently as a single entity in the World Health Organization classification of Head and Neck Tumors 2017, with only 14 cases published to date. The biological characteristics of sclerosing odontogenic carcinoma remain indistinct because of its rarity; however, it appears to be locally aggressive, with no regional or distant metastasis reported to date.
CASE SUMMARY
We reported a case of sclerosing odontogenic carcinoma of the maxilla in a 62-year-old woman, who presented with an indolent right palatal swelling, which progressively increased in size over 7 years. Right subtotal maxillectomy with surgical margins of approximately 1.5 cm was performed. The patient remained disease free for 4 years following the ablation surgery. Diagnostic workups, treatment, and therapeutic outcomes were discussed.
CONCLUSION
More cases are needed to further characterize this entity, understand its biological behavior, and justify the treatment protocols. Resection with wide margins of approximately 1.0 to 1.5 cm is proposed, while neck dissection, post-operative radiotherapy, or chemotherapy are deemed unnecessary.
Core Tip: Sclerosing odontogenic carcinoma is a rare disease entity with only 14 cases published to date, this case report will further substantiate the understanding to this disease and the management protocols.
