Published online Feb 26, 2023. doi: 10.12998/wjcc.v11.i6.1365
Peer-review started: October 14, 2022
First decision: January 5, 2023
Revised: January 18, 2023
Accepted: February 7, 2023
Article in press: February 7, 2023
Published online: February 26, 2023
Endometriosis is a common gynecological disorder that affects women of reproductive age. It is characterized by a cancer-like invasion of the extra-uterine endometrium and exhibits a strong association with ovarian clear cell cancer and endometrioid cancer. Endometriosis-associated fallopian tube endometrioid adenocarcinoma synchronized with endometrial adenocarcinoma was rarely reported.
A 49-year-old woman was referred to our hospital complaining about abnormal vaginal bleeding for three years following unsatisfactory medication. Intraoperative frozen sections unexpectedly unveiled an endometrioid cancer of the left fallopian tube with superficial invasion surrounded by diffuse endometriosis synchronized with endometrioid endometrial cancer.
It was difficult to make a differential diagnosis when confronted with incidental findings of fallopian tube cancer lesions synchronized with endometrial cancer. The key differential diagnosis of primary endometriosis-associated endometrioid adenocarcinoma of the fallopian tube from endometrial adenocarcinoma invol
Core Tip: The key to distinguishing primary endometriosis-associated fallopian tube cancer from fallopian tube involvement in endometrial cancer was the pathological identification of malignant transformation in endometriosis-associated fallopian tube tumors.