Liao Y, Li YJ, Hu XW, Wen R, Wang P. Benign lymphoepithelial cyst of parotid gland without human immunodeficiency virus infection: A case report . World J Clin Cases 2023; 11(4): 931-937 [PMID: 36818610 DOI: 10.12998/wjcc.v11.i4.931]
Corresponding Author of This Article
Pan Wang, MD, Chief Doctor, Director, Professor, Department of Nuclear Medicine, Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Huichuan District, Zunyi 563003, Guizhou Province, China. 1298178828@qq.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Feb 6, 2023; 11(4): 931-937 Published online Feb 6, 2023. doi: 10.12998/wjcc.v11.i4.931
Benign lymphoepithelial cyst of parotid gland without human immunodeficiency virus infection: A case report
Yan Liao, Yan-Jie Li, Xian-Wen Hu, Rui Wen, Pan Wang
Yan Liao, Xian-Wen Hu, Rui Wen, Pan Wang, Department of Nuclear Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Yan-Jie Li, Department of Critical Care Medicine, The Second Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Author contributions: Liao Y and Li YJ contributed to the study conception and writing; Liao Y and Hu XW contributed to the collection of pathological findings; Hu XW and Wen R contributed to the analysis; Li YJ collected data; Wang P reviewed and revised the first draft; all authors read and approved the final version of the manuscript.
Supported byZunyi Medical College Research Start Fund, No. 2017CK-1130-038.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Pan Wang, MD, Chief Doctor, Director, Professor, Department of Nuclear Medicine, Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Huichuan District, Zunyi 563003, Guizhou Province, China. 1298178828@qq.com
Received: October 1, 2022 Peer-review started: October 1, 2022 First decision: November 30, 2022 Revised: December 13, 2022 Accepted: January 10, 2023 Article in press: January 10, 2023 Published online: February 6, 2023 Processing time: 128 Days and 0.2 Hours
Abstract
BACKGROUND
Benign lymphoepithelial cyst (BLEC) of the parotid gland is a rare benign embryonic-dysplastic cystic tumor in the anterolateral neck that occurs most commonly in human immunodeficiency virus (HIV)-positive adults and rarely in non-acquired immune deficiency syndrome patients. The main presentation is a slow-growing, painless mass, and secondary infection may cause acute inflammatory symptoms.
CASE SUMMARY
A 44-year-old Chinese male patient presented with a 1-year history of a mass in the left side of the neck. On physical examination, a mass similar in size and shape to a quail egg was found in the left parotid gland. The mass was tough, without tenderness, and easily moveable. The results of HIV tests, including antibody and nucleic acid tests and CD4+ T cell examination, were negative. Imaging examination revealed a left parotid gland mass. The patient underwent surgical treatment, and BLEC was diagnosed based on postoperative pathology. After 2 years of follow-up, the patient survived well without related discomfort.
CONCLUSION
The detailed characteristics of a BLEC in a patient without HIV infection contribute to an improved understanding of this rare disease.
Core Tip: Benign lymphoepithelial cyst (BLEC) of the parotid gland is a rare lesion seldom found in non-acquired immune deficiency syndrome patients. BLECs are benign embryonic dysplastic cystic tumors that typically occur in the anterolateral part of the neck. We present a case of BLEC of the parotid gland in a non-human immunodeficiency virus -infected patient in order to improve clinicians’ understanding of the disease.
