Zhou Y, Tong JL, Peng AH, Xu SY. Comparison of drug concentrations in blood and gastric lavage fluid before and after gastric lavage: A case report. World J Clin Cases 2023; 11(31): 7680-7683 [PMID: 38078128 DOI: 10.12998/wjcc.v11.i31.7680]
Corresponding Author of This Article
Shu-Yun Xu, MD, Doctor, Department of Emergency Medicine and West China School of Nursing, Laboratory of Emergency Medicine, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. xshuyun2023@163.com
Research Domain of This Article
Emergency Medicine
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 6, 2023; 11(31): 7680-7683 Published online Nov 6, 2023. doi: 10.12998/wjcc.v11.i31.7680
Comparison of drug concentrations in blood and gastric lavage fluid before and after gastric lavage: A case report
Yue Zhou, Jia-Le Tong, Ai-Hua Peng, Shu-Yun Xu
Yue Zhou, Jia-Le Tong, Ai-Hua Peng, Shu-Yun Xu, Department of Emergency Medicine and West China School of Nursing, Laboratory of Emergency Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Yue Zhou, Jia-Le Tong, Ai-Hua Peng, Shu-Yun Xu, Disaster Medical Center, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Zhou Y contributed to manuscript writing and editing, and data collection; Peng AH and Tong JL contributed to data analysis; Xu SY contributed to conceptualization and supervision; All authors have read and approved the final manuscript.
Supported byEarly Diagnosis of Venom-Induced Ventricular Fascia Syndrome Based on High Frequency Ultrasound and Shear Wave Elastography, No. 2021YFS0189.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shu-Yun Xu, MD, Doctor, Department of Emergency Medicine and West China School of Nursing, Laboratory of Emergency Medicine, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. xshuyun2023@163.com
Received: August 24, 2023 Peer-review started: August 24, 2023 First decision: September 28, 2023 Revised: October 2, 2023 Accepted: October 17, 2023 Article in press: October 17, 2023 Published online: November 6, 2023 Processing time: 73 Days and 21.7 Hours
Abstract
BACKGROUND
Gastric lavage (GL) is one of the most important early therapies to remove unabsorbed toxins from the gastrointestinal tract. However, the details of performing gastric lavage remain to be established. There is controversy in clinical practice regarding individual choice of the timing of GL and its efficiency.
CASE SUMMARY
We report the case of a young woman who presented to the Emergency Department with drug intoxication for four hours. We used the latest toxicological screening techniques to compare drug concentrations in the patient's blood and gastric lavage fluid before and after gastric lavage. The results confirmed that gastric lavage was effective in reducing drug concentrations in the stomach; a small amount of drug remained in the stomach at the end of gastric lavage.
CONCLUSION
Gastric lavage is effective in reducing drug concentrations in the stomach, with a small amount of drug remaining in the stomach at the end of gastric lavage.
Core Tip: Gastric lavage (GL) is one of the most critical early therapies for oral poisoning, but details of the treatment protocol remain to be established. Controversies remain in clinical practice regarding individual choice of the GL timing and its efficiency. We report the case of a young woman who presented to the Emergency Department with a drug intoxication for four hours. We used the latest toxicological screening techniques to compare drug concentrations in the patient's blood and GL fluid before and after GL. The results confirm that GL is effective at reducing drug concentrations in the stomach, and we found that a small amount of drug remained in the stomach when the indication for termination of GL was judged conventionally.
