Seo J, Lee J, Shin YH, Jang AY, Suh SY. Acute myocardial infarction after initially diagnosed with unprovoked venous thromboembolism: A case report. World J Clin Cases 2023; 11(30): 7497-7501 [PMID: 37969461 DOI: 10.12998/wjcc.v11.i30.7497]
Corresponding Author of This Article
Soon Yong Suh, MD, PhD, Associate Professor, Department of Cardiology, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon 405-760, South Korea. ssy@gilhospital.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 26, 2023; 11(30): 7497-7501 Published online Oct 26, 2023. doi: 10.12998/wjcc.v11.i30.7497
Acute myocardial infarction after initially diagnosed with unprovoked venous thromboembolism: A case report
Jeongduk Seo, Joonpyo Lee, Yong Hoon Shin, Albert Youngwoo Jang, Soon Yong Suh
Jeongduk Seo, Joonpyo Lee, Yong Hoon Shin, Albert Youngwoo Jang, Soon Yong Suh, Department of Cardiology, Gachon University Gil Medical Center, Incheon 405-760, South Korea
Author contributions: Seo J, Jang Y, and Suh SY contributed to conceptualization, design and methodology, and visualization; Seo J, Lee J, Shin YH, Jang Y, and Suh SY were responsible for validation; Seo J, Jang Y, and Suh SY participated in the original draft preparation; Seo J, Jang Y, and Suh SY reviewed and edited the manuscript; Suh SY contributed to the supervision and project administration; All authors issued their final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and accompanying images.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Soon Yong Suh, MD, PhD, Associate Professor, Department of Cardiology, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon 405-760, South Korea. ssy@gilhospital.com
Received: August 23, 2023 Peer-review started: August 23, 2023 First decision: September 26, 2023 Revised: October 3, 2023 Accepted: October 16, 2023 Article in press: October 16, 2023 Published online: October 26, 2023 Processing time: 63 Days and 2.4 Hours
Abstract
BACKGROUND
Protein C deficiency is typically associated with venous thromboembolism; however, arterial thrombosis has been reported in several cases. We report the case of a patient with pulmonary thromboembolism and deep vein thrombosis following acute myocardial infarction with high thrombus burden.
CASE SUMMARY
A 40-year-old man was diagnosed with pulmonary thromboembolism and deep vein thrombosis without any provoking factors. The patient was treated with anticoagulants for six months, which were then discontinued. Three months after the discontinuation of anticoagulant therapy, the patient was hospitalized with chest pain and diagnosed with acute myocardial infarction with high thrombus burden. Additional tests revealed protein C deficiency associated with thrombophilia. The patient was treated with anticoagulants combined with dual antiplatelet agents for 1 year after percutaneous coronary intervention, and no recurrent events were reported during a follow-up period of 5 years.
CONCLUSION
Recurrent thromboembolic events including acute myocardial infarction with thrombus should be considered an alarming sign of thrombophilia.
Core Tip: This case report outlines a 40-year-old male patient who experienced a sequence of thromboembolic events, including pulmonary thromboembolism, deep vein thrombosis, and acute myocardial infarction, all accompanied by significant thrombus burdens.
