Xiao QF, Li J, Tang B, Zhu YQ. Testicular mixed germ cell tumor: A case report. World J Clin Cases 2023; 11(28): 6902-6907 [PMID: 37901019 DOI: 10.12998/wjcc.v11.i28.6902]
Corresponding Author of This Article
Yu-Qing Zhu, MD, MMed, Associate Chief Physician, Professor, Department of International General Practice, China-Japan Friendship Hospital, No. 2 Yinghua Street, Chaoyang District, Beijing 100029, China. circe_qi@126.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2023; 11(28): 6902-6907 Published online Oct 6, 2023. doi: 10.12998/wjcc.v11.i28.6902
Testicular mixed germ cell tumor: A case report
Qi-Fan Xiao, Jie Li, Bin Tang, Yu-Qing Zhu
Qi-Fan Xiao, Bin Tang, Yu-Qing Zhu, Department of International General Practice, China-Japan Friendship Hospital, Beijing 100029, China
Jie Li, Department of General Practice, Xinggu Street Community Health Service Center, Beijing 101200, China
Author contributions: Zhu YQ designed the research study; Xiao QF, Li J, and Tang B performed the research; Li J contributed new reagents and analytic tools; Xiao QF, Li J, and Tang B analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: Consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Qing Zhu, MD, MMed, Associate Chief Physician, Professor, Department of International General Practice, China-Japan Friendship Hospital, No. 2 Yinghua Street, Chaoyang District, Beijing 100029, China. circe_qi@126.com
Received: July 11, 2023 Peer-review started: July 11, 2023 First decision: August 24, 2023 Revised: August 30, 2023 Accepted: September 14, 2023 Article in press: September 14, 2023 Published online: October 6, 2023 Processing time: 76 Days and 8.7 Hours
Abstract
BACKGROUND
Testicular mixed germ cell tumors (TMGCTs) are rare malignant tumors that are more common in men aged 20–40 years. TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis. Their onset is undetectable; thus, early diagnosis is challenging. However, early recognition and diagnosis substantially improve patient prognosis.
CASE SUMMARY
We evaluated a rare case of TMGCT in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis instead of testicular enlargement and pain, which may easily lead to misdiagnosis. We report the clinical signs and symptoms, histopathological characteristics, and immunohistochemical results of this case of malignant TMGCT.
CONCLUSION
Our case, which was typical with multiple components, along with a literature review, may serve as a basis for early diagnosis.
Core Tip: We evaluated a rare case of testicular mixed germ cell tumor (TMGCT) in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis, instead of testicular enlargement and pain, which may easily lead to misdiagnosis. We report the clinical signs and symptoms, histopathological characteristics, and immunohistochemistry findings of this case of malignant TMGCT. Our case, which presented multiple components typical of TMGCT, along with a literature review, may serve as a basis for the early recognition and diagnosis of this disease.
