Lin X, Feng NY, Lei YJ. Diagnosis and treatment of McCune-Albright syndrome: A case report. World J Clin Cases 2023; 11(28): 6817-6822 [PMID: 37901000 DOI: 10.12998/wjcc.v11.i28.6817]
Corresponding Author of This Article
Ning-Yu Feng, Doctor, Additional Professor, Chief Physician, Department of Otolaryngology, The First People's Hospital of Yinchuan, No. 2 Liqun West Street, Xingqing District, Yinchuan 750000, Ningxia Hui Autonomous Region, China. fengningyu@126.com
Research Domain of This Article
Dentistry, Oral Surgery & Medicine
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2023; 11(28): 6817-6822 Published online Oct 6, 2023. doi: 10.12998/wjcc.v11.i28.6817
Diagnosis and treatment of McCune-Albright syndrome: A case report
Xin Lin, Ning-Yu Feng, Yu-Jin Lei
Xin Lin, Yu-Jin Lei, Department of Otolaryngology, The Second Affiliated Clinical College of Ningxia Medical University, Yinchuan 750000, Ningxia Hui Autonomous Region, China
Ning-Yu Feng, Department of Otolaryngology, The First People's Hospital of Yinchuan, Yinchuan 750000, Ningxia Hui Autonomous Region, China
Author contributions: Lin X designed and wrote the manuscript; Feng NY supervised and edited the manuscript; Lei YJ collected the patient’s clinical data; all authors issued final approval for the version to be submitted.
Informed consent statement: The publication of this report obtained the informed consent of the parents of the patient.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ning-Yu Feng, Doctor, Additional Professor, Chief Physician, Department of Otolaryngology, The First People's Hospital of Yinchuan, No. 2 Liqun West Street, Xingqing District, Yinchuan 750000, Ningxia Hui Autonomous Region, China. fengningyu@126.com
Received: July 1, 2023 Peer-review started: July 1, 2023 First decision: August 17, 2023 Revised: August 26, 2023 Accepted: September 11, 2023 Article in press: September 11, 2023 Published online: October 6, 2023 Processing time: 85 Days and 19.2 Hours
Abstract
BACKGROUND
McCune-Albright syndrome (MAS) is extremely rare clinically. We here report a case of MAS with severe symptoms that have not been reported previously.
CASE SUMMARY
A 10-year-old boy attended our outpatient clinic due to craniofacial malformations found two years ago. He underwent temporal bone computed tomography and digital radiography photography. Based on a literature review combined with the patient's medical history and imaging examination findings, he was diagnosed with multiple fibrous dysplasia of bone. As the clinical symptoms related to MAS in this patient were not obvious, he was only followed up and not given any special treatment.
CONCLUSION
The unique clinical manifestations in this MAS patient may be related to mutations in the GNAS gene.
Core Tip: McCune-Albright syndrome is extremely rare in clinical practice, which is mainly manifested as fibrous dysplasia, café-au-lait skin spots, and precocious puberty. The clinical manifestations of the present patient were typical, with severe symptoms that have not been reported previously. This case report may provide reference for the diagnosis and treatment of this disease.
