Zhu YQ, Zhao GC, Zheng CX, Yuan L, Yuan GB. Managing spindle cell sarcoma with surgery and high-intensity focused ultrasound: A case report. World J Clin Cases 2023; 11(27): 6551-6557 [PMID: 37900255 DOI: 10.12998/wjcc.v11.i27.6551]
Corresponding Author of This Article
Geng-Biao Yuan, MD, PhD, Chief Physician, Department of Nuclear Medicin, The Second Affiliated Hospital of Chongqing Medical University, No. 288 Chayuan Astronomical Avenue, Nanan District, Chongqing 400010, China. 300784@hospital.cqmu.edu.cn
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 26, 2023; 11(27): 6551-6557 Published online Sep 26, 2023. doi: 10.12998/wjcc.v11.i27.6551
Managing spindle cell sarcoma with surgery and high-intensity focused ultrasound: A case report
Ying-Qiong Zhu, Gan-Chao Zhao, Chen-Xi Zheng, Lei Yuan, Geng-Biao Yuan
Ying-Qiong Zhu, Department of Endocrinology, People’s Hospital of Fengjie, Fengjie 404600, Chongqing, China
Gan-Chao Zhao, Department of Oncology, People’s Hospital of Fengjie, Fengjie 404600, Chongqing, China
Chen-Xi Zheng, Geng-Biao Yuan, Department of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
Lei Yuan, Department of Endocrinology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
Author contributions: Zhu YQ prepared the manuscript; Yuan GB served as the corresponding author and provided manuscript review; Zhao GC and Zheng CX were responsible for the clinical management and patient follow-up; Yuan L contributed to the manuscript revision and engaged in helpful discussions; All authors contributed to the manuscript and approved the submitted version.
Informed consent statement: This study participant provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Geng-Biao Yuan, MD, PhD, Chief Physician, Department of Nuclear Medicin, The Second Affiliated Hospital of Chongqing Medical University, No. 288 Chayuan Astronomical Avenue, Nanan District, Chongqing 400010, China. 300784@hospital.cqmu.edu.cn
Received: June 6, 2023 Peer-review started: June 6, 2023 First decision: August 8, 2023 Revised: August 18, 2023 Accepted: August 31, 2023 Article in press: August 31, 2023 Published online: September 26, 2023 Processing time: 106 Days and 6.9 Hours
Abstract
BACKGROUND
Undifferentiated pleomorphic sarcomas, also known as spindle cell sarcomas, are a relatively uncommon subtype of soft tissue sarcomas in clinical practice.
CASE SUMMARY
We present a case report of a 69-year-old female patient who was diagnosed with undifferentiated spindle cell soft tissue sarcoma on her left thigh. Surgical excision was initially performed, but the patient experienced a local recurrence following multiple surgeries and radioactive particle implantations. High-intensity focused ultrasound (HIFU) was subsequently administered, resulting in complete ablation of the sarcoma without any significant complications other than bone damage at the treated site. However, approximately four months later, the patient experienced a broken lesion at the original location. After further diagnostic workup, the patient underwent additional surgery and is currently stable with a good quality of life.
CONCLUSION
HIFU has shown positive outcomes in achieving local control of limb spindle cell sarcoma, making it an effective non-invasive treatment option.
Core Tip: High-intensity focused ultrasound (HIFU) has the potential to be a reliable, minimally invasive technique that could revolutionize cancer treatment. Although relatively rare, limb spindle cell sarcomas can be effectively controlled by non-invasive treatment, as demonstrated in this case report. Continued advancements in HIFU technology will improve its effectiveness and benefit patients.
