Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2023; 11(26): 6159-6164
Published online Sep 16, 2023. doi: 10.12998/wjcc.v11.i26.6159
Early diagnosis of renal pelvis villous adenoma: A case report
Liang-Liang Li, Pei-Xing Song, De-Fu Xing, Kun Liu
Liang-Liang Li, Pei-Xing Song, De-Fu Xing, Kun Liu, Department of Urology, Fuyang Hospital of Anhui Medical University, Fuyang 236000, Anhui Province, China
Author contributions: Li LL collected the data and drafted the manuscript; Song PX reviewed the literature and contributed to manuscript drafting; Liu K contributed to revision of the manuscript; All authors reviewed and approved the final manuscript.
Supported by Anhui Province Key Clinical Specialty (Urology 2022).
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Pei-Xing Song, MD, Chief Doctor, Department of Urology, Fuyang Hospital of Anhui Medical University, No. 99 Huangshan Road, Yinzhou District, Fuyang 236000, Anhui Province, China. uro_spx@163.com
Received: April 7, 2023
Peer-review started: April 7, 2023
First decision: July 3, 2023
Revised: July 12, 2023
Accepted: July 25, 2023
Article in press: July 25, 2023
Published online: September 16, 2023
Processing time: 153 Days and 20 Hours
Abstract
BACKGROUND

Villous adenoma is a rare tumor in the urinary system that usually occurs in the bladder. It is extremely uncommon in the renal pelvis. Most of the previously reported cases have been diagnosed with severe hydronephrosis associated with renal parenchyma atrophy prior to surgery. Because of its rarity, available information on the pathogenesis, diagnosis, treatment and prognosis of the disease is limited. We reported a case of kidney stones with hydronephrosis. During percutaneous nephroscopic lithotripsy, a renal pelvis tumor was found. Biopsy confirmed that the tumor was a villous adenoma of the renal pelvis.

CASE SUMMARY

A 68-year-old female was admitted to the hospital due to right kidney stones with right hydronephrosis. After admission, a urinary system plain computed tomography scan was performed, which revealed right kidney stones with right hydronephrosis and right upper ureteral dilatation. Multiple new cauliflower-like papillary masses were then discovered in the renal pelvis and calyces during right percutaneous nephroscopic lithotripsy. Biopsy results indicated villous adenoma with high-grade glandular intraepithelial neoplasia. The patient underwent laparoscopic radical resection of the right kidney and ureter. Based on histopathological and immunohistochemical examination, the patient was diagnosed with villous adenoma without adenocarcinoma.

CONCLUSION

Villous adenoma is rare in the urinary system. We reported a case of renal pelvis villous adenoma, which may provide useful information for the early diagnosis and treatment of this tumor.

Keywords: Villous adenoma; Renal pelvis; Primarily; Hydronephrosis; Early diagnosis; Case report

Core Tip: Villous adenoma is a rare tumor in the urinary system. We reported a patient who was admitted to the hospital due to right kidney stones with right hydronephrosis. Biopsy indicated a villous adenoma with high-grade glandular intraepithelial neoplasia after right percutaneous nephroscopic lithotripsy. The patient underwent laparoscopic radical resection of the right kidney and ureter. Based on histopathological and immunohistochemical results, the patient was diagnosed with villous adenoma without adenocarcinoma.