Aydin OC, Aydin S, Guney HZ. Defining the awareness and attitude of the clinicians through pharmacovigilance in Turkey. World J Clin Cases 2023; 11(20): 4865-4873 [PMID: 37583988 DOI: 10.12998/wjcc.v11.i20.4865]
Corresponding Author of This Article
Ozlem Celik Aydin, MD, Doctor, Department of Medical Pharmacology, Gazi University Faculty of Medicine, Besevler, Ankara 06500, Turkey. ozlemclk_89@hotmail.com
Research Domain of This Article
Pharmacology & Pharmacy
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 16, 2023; 11(20): 4865-4873 Published online Jul 16, 2023. doi: 10.12998/wjcc.v11.i20.4865
Defining the awareness and attitude of the clinicians through pharmacovigilance in Turkey
Ozlem Celik Aydin, Sonay Aydin, Hakkı Zafer Guney
Ozlem Celik Aydin, Sonay Aydin, Hakkı Zafer Guney, Department of Medical Pharmacology, Gazi University Faculty of Medicine, Ankara 06500, Turkey
Author contributions: Aydin OC and Guney HZ put forward the concept; Aydin OC was responsible for designing; Guney HZ were responsible for supervision; Aydin S, Aydin OC and Guney HZ did the literature search and reviewed the manuscript critically; Aydin S and Aydin OC were responsible for materials and wrote the manuscript; All authors have read and approved the final manuscript.
Institutional review board statement: This cross-sectional analytical investigation was approved by the Gazi University Clinical Research Ethics Committee, No. 25901600-604.01.01-16.
Informed consent statement: The study included everyone who agreed to participate in the survey.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data will be shared with the relevant parties upon request atozlemclk_89@hotmail.com.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ozlem Celik Aydin, MD, Doctor, Department of Medical Pharmacology, Gazi University Faculty of Medicine, Besevler, Ankara 06500, Turkey. ozlemclk_89@hotmail.com
Received: February 21, 2023 Peer-review started: February 21, 2023 First decision: April 10, 2023 Revised: May 1, 2023 Accepted: June 9, 2023 Article in press: June 9, 2023 Published online: July 16, 2023 Processing time: 140 Days and 11.5 Hours
Abstract
BACKGROUND
Pharmacovigilance (PV) is the activities and scientific studies conducted to detect, evaluate, understand or prevent adverse reactions and other drug-related problems.
AIM
To define the awareness and experiences of the clinicians on PV and adverse drug reactions (ADRs) in Turkey.
METHODS
The study was cross-sectional and analytical. Data were obtained through a questionnaire. The questionnaire was sent via e-mail. The survey was sent to 2030 physicians and 670 participated.
RESULTS
The most appropriate definition of PV was correctly defined by 53.9% of the participants. The most important goal of PV was correctly defined by 54.9% of the participants, and 27.3% of the participants were aware of the Turkish Pharmacovigilance Center. Nonsurgical physicians had better PV knowledge than surgical physicians. A total of 80.9% of the physicians who encountered ADRs, filled in the ADR notification form, and 8.8% received training on how to fill in the form. PV knowledge of the clinicians was not sufficient. Although half of the physicians encountered ADRs, the rates of seeing and filling in the ADR form were low.
CONCLUSION
Few of the physicians followed the current information about PV. The results provide more comprehensive data on PV practices and ADR reporting at a national level.
Core tip: Pharmacovigilance (PV) is the activities and scientific studies conducted to detect, evaluate, understand or prevent adverse reactions and other drug-related problems. This study define the awareness and experiences of clinicians about PV and adverse drug reactions (ADRs) in Turkey. PV knowledge level of the physicians was not sufficient. The results provide more comprehensive data on PV practices and ADR reporting at a national level.
