Tong M, Zhang BC, Jia FY, Wang J, Liu JH. Hepatic inflammatory myofibroblastic tumor: A case report. World J Clin Cases 2023; 11(18): 4318-4325 [PMID: 37449218 DOI: 10.12998/wjcc.v11.i18.4318]
Corresponding Author of This Article
Jing-Hua Liu, MD, PhD, Academic Editor, Assistant Professor, Chief Financial Officer, Department of Hepatobiliary Surgery and Minimally Invasive Institute of Digestive Surgery and Prof. Cai’s Laboratory, Linyi People’s Hospital, No. 27 Jiefang East Road, Linyi 276000, Shandong Province, China. jinghualiu1982@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 26, 2023; 11(18): 4318-4325 Published online Jun 26, 2023. doi: 10.12998/wjcc.v11.i18.4318
Hepatic inflammatory myofibroblastic tumor: A case report
Meng Tong, Bo-Cheng Zhang, Fei-Yu Jia, Jing Wang, Jing-Hua Liu
Meng Tong, Bo-Cheng Zhang, Department of General Surgery, Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China
Fei-Yu Jia, Graduate Management Office, Education and Teaching Department, Linyi People’s Hospital, Linyi 276000, Shandong Province, China
Jing Wang, Department of Radiology, Linyi People’s Hospital, Linyi 276000, Shandong Province, China
Jing-Hua Liu, Department of Hepatobiliary Surgery and Minimally Invasive Institute of Digestive Surgery and Prof. Cai’s Laboratory, Linyi People’s Hospital, Linyi 276000, Shandong Province, China
Author contributions: Tong M and Zhang BC contributed to manuscript writing and editing and data collection; Jia FY contributed to data analysis; Wang J and Liu JH contributed to conceptualization and supervision; all authors read and approved the final manuscript.
Supported byShandong Provincial Natural Science Foundation of China, No. ZR2021MH033; Postgraduates Foundation of Linyi People’s Hospital (Tong Meng).
Informed consent statement: Written informed consent was obtained from the patient for the publication of this case and images.
Conflict-of-interest statement: The authors declare having no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jing-Hua Liu, MD, PhD, Academic Editor, Assistant Professor, Chief Financial Officer, Department of Hepatobiliary Surgery and Minimally Invasive Institute of Digestive Surgery and Prof. Cai’s Laboratory, Linyi People’s Hospital, No. 27 Jiefang East Road, Linyi 276000, Shandong Province, China. jinghualiu1982@163.com
Received: February 2, 2023 Peer-review started: February 2, 2023 First decision: March 24, 2023 Revised: April 15, 2023 Accepted: May 23, 2023 Article in press: May 23, 2023 Published online: June 26, 2023 Processing time: 144 Days and 13.2 Hours
Abstract
BACKGROUND
Hepatic inflammatory myofibroblastic tumor (HIMT) is a rare type of hepatic tumor. It is always misdiagnosed and mistreated because it is primarily found with no obvious specific manifestation, and its imaging findings are diverse.
CASE SUMMARY
Here, we report a case of HIMT that was initially diagnosed as liver malignancy but was confirmed as HIMT by histopathology after hepatectomy. Mostly, HIMTs are infiltrated with plasma cells and stain positively for anaplastic lymphoma kinase on immunohistochemistry as well as for some other kinases.
CONCLUSION
HIMT can be treated with single nonsteroidal anti-inflammatory drugs and without surgery when it is diagnosed accurately. Because the etiology of HIMT is unknown and the diagnosis is difficult, the pathogenesis and clinical process need to be further studied.
Core Tip: Hepatic inflammatory myofibroblastic tumor (HIMT) is a rare type of hepatic tumor. HIMT are found during physical examination with no obvious specific manifestation. The imaging manifestations of HIMT are diverse, making diagnosis through imaging examination difficult. Accurate diagnosis of HIMT is obtained by histopathology of the resected/biopsied specimen. We reported a case of HIMT initially diagnosed as liver malignancy. HIMT can be treated with single nonsteroidal anti-inflammatory drugs when it is diagnosed accurate. Through this case analysis and literature review, further data was provided to aid in the early diagnosis and initial treatment of this tumor.
