Cho YH, Lee Y, Choi JI, Lee SR, Lee SY. Weight loss maintenance after bariatric surgery. World J Clin Cases 2023; 11(18): 4241-4250 [PMID: 37449236 DOI: 10.12998/wjcc.v11.i18.4241]
Corresponding Author of This Article
Sang Yeoup Lee, MD, PhD, Professor, Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Geumo-ro 20, Mulgeum-eup, Yangsan 50612, South Korea. saylee@pnu.edu
Research Domain of This Article
Surgery
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 26, 2023; 11(18): 4241-4250 Published online Jun 26, 2023. doi: 10.12998/wjcc.v11.i18.4241
Weight loss maintenance after bariatric surgery
Young-Hye Cho, Youngin Lee, Jung In Choi, Sae Rom Lee, Sang Yeoup Lee
Young-Hye Cho, Department of Family Medicine, Pusan National University School of Medicine, Yangsan 50612, South Korea
Young-Hye Cho, Youngin Lee, Jung In Choi, Sae Rom Lee, Department of Family Medicine, Pusan National University Yangsan Hospital, Yangsan 50612, South Korea
Sang Yeoup Lee, Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan 50612, South Korea
Sang Yeoup Lee, Department of Medical Education, Pusan National University School of Medicine, Yangsan 50612, South Korea
Author contributions: Lee SY and Cho YH contributed to the study design; Lee SY is the corresponding author of this manuscript; Lee Y, Choi JI, and Lee SR contributed to data collection; Lee SY and Cho YH contributed to data analysis and interpretation and wrote the article; Lee SY contributed to article revision and statistical analysis; and all authors have read and approved the final version of the article.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sang Yeoup Lee, MD, PhD, Professor, Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Geumo-ro 20, Mulgeum-eup, Yangsan 50612, South Korea. saylee@pnu.edu
Received: February 28, 2023 Peer-review started: February 28, 2023 First decision: March 24, 2023 Revised: April 28, 2023 Accepted: May 25, 2023 Article in press: May 25, 2023 Published online: June 26, 2023 Processing time: 118 Days and 0.5 Hours
Abstract
Metabolic and bariatric surgery (MBS) is an effective treatment for patients with morbid obesity and its comorbidities. However, many patients experience weight regain (WR) after achieving their nadir weight. Establishing the definition of WR is challenging as postoperative WR has various definitions. Risk factors for WR after MBS include anatomical, racial, hormonal, metabolic, behavioral, and psychological factors, and evaluating such factors preoperatively is necessary. Long-term regular follow-up and timely treatment by a multidisciplinary team are important because WR after surgery is multi-factorial. Although lifestyle interventions that focus on appropriate dietary education, physical activity education or interventions, and behavioral psychological interventions are suggested, more well-designed studies are needed because studies evaluating intervention methods and the effectiveness of WR prevention are lacking. Anti-obesity drugs can be used to prevent and manage patients with WR after MBS; however, more research is needed to determine the timing, duration, and type of anti-obesity drugs used to prevent WR.
Core Tip: Metabolic and bariatric surgery (MBS) is an evidence-based treatment for morbid obesity that contributes to sustainable weight loss over long-term periods. Unfortunately, post-MBS weight regain (WR) still occurs at a considerable rate, and its incidence continues to increase annually. This review summarizes updated information on weight trajectories after MBS, definitions of postoperative WR, factors contributing to postsurgical WR, and strategies to prevent WR after sleeve gastrectomy or Roux-en-Y gastric bypass.
