Algahtani FN, Almohareb R, Aljamie M, Alkhunaini N, ALHarthi SS, Barakat R. Application of advanced platelet-rich fibrin for through-and-through bony defect during endodontic surgery: Three case reports and review of the literature. World J Clin Cases 2023; 11(17): 4168-4178 [PMID: 37388804 DOI: 10.12998/wjcc.v11.i17.4168]
Corresponding Author of This Article
Reem Barakat, DDS, MSc, Assistant Professor, Department of Clinical Dental Sciences, College of Dentistry, Princess Nourah Bint Abdulrahman University, Airport Road, Riyadh 11671, Saudi Arabia. rmbarakat@pnu.edu.sa
Research Domain of This Article
Dentistry, Oral Surgery & Medicine
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 16, 2023; 11(17): 4168-4178 Published online Jun 16, 2023. doi: 10.12998/wjcc.v11.i17.4168
Application of advanced platelet-rich fibrin for through-and-through bony defect during endodontic surgery: Three case reports and review of the literature
Fahda N Algahtani, Rahaf Almohareb, Reem Barakat, Department of Clinical Dental Sciences, College of Dentistry, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia
Manar Aljamie, Department of Endodontics, Vision Colleges of Dentistry and Nursing, Riyadh 11671, Saudi Arabia
Nouf Alkhunaini, Department of Dental, Specialized Medical Center Hospitals, Riyadh 11671, Saudi Arabia
Shatha Subhi ALHarthi, Department of Preventive Dental Sciences, College of Dentistry, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia
Author contributions: Algahtani FN, Aljamie M, and Alkhunaini N contributed to manuscript writing, editing, and data collection; Almohareb RA and Alharthi SS contributed to data collection; Barakat RM contributed to writing and editing; and all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Reem Barakat, DDS, MSc, Assistant Professor, Department of Clinical Dental Sciences, College of Dentistry, Princess Nourah Bint Abdulrahman University, Airport Road, Riyadh 11671, Saudi Arabia. rmbarakat@pnu.edu.sa
Received: March 23, 2023 Peer-review started: March 23, 2023 First decision: April 26, 2023 Revised: May 1, 2023 Accepted: May 15, 2023 Article in press: May 15, 2023 Published online: June 16, 2023 Processing time: 81 Days and 1.5 Hours
Abstract
BACKGROUND
The use of advanced platelet-rich fibrin (A-PRF) membranes for guided bone and tissue regeneration in through-and-through defects after endodontic surgery was explored in three cases.
CASE SUMMARY
Herein, three patients presented to the endodontic clinic suffering from apical periodontitis, associated with large bone resorption and related to previously endodontically treated teeth. Periapical surgery was indicated in these cases and the osteotomy site was covered by A-PRF membrane. Cone-beam computed tomography (CBCT) was used to assess the cases before and after the surgery.
CONCLUSION
Four months post-surgery, the recall CBCT scan showed complete obliteration of the osteotomy with newly formed bone. A-PRF membrane showed promising results and was an advantageous addition to surgical endodontic treatment.
Core Tip: The use of advanced platelet-rich fibrin (A-PRF) membrane in endodontic surgery in conjunction with cone-beam computed tomography helped establish bone healing after short-term follow-up. The A-PRF membrane’s low expense, low risk of post-surgical infection, and foreign body rejection makes it a useful adjunct to surgical endodontic treatment.
