Jung HS, Kim HJ, Kim KW. Intraoperative photodynamic therapy for tracheal mass in non-small cell lung cancer: A case report. World J Clin Cases 2023; 11(16): 3915-3920 [PMID: 37383135 DOI: 10.12998/wjcc.v11.i16.3915]
Corresponding Author of This Article
Kwan Wook Kim, MD, PhD, Surgeon, Department of Thoracic and Cardiovascular Surgery, CHA Bundang Medical Center, 59, Yatap-ro, Bundang-gu, SeongnamJ-si 13496, South Korea. mujin100km@cha.ac.kr
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 6, 2023; 11(16): 3915-3920 Published online Jun 6, 2023. doi: 10.12998/wjcc.v11.i16.3915
Intraoperative photodynamic therapy for tracheal mass in non-small cell lung cancer: A case report
Hee Suk Jung, Hyun Jung Kim, Kwan Wook Kim
Hee Suk Jung, Hyun Jung Kim, Kwan Wook Kim, Department of Thoracic and Cardiovascular Surgery, CHA Bundang Medical Center, Seongnam-si 13496, South Korea
Author contributions: Jung HS and Kim KW wrote and edited the manuscript and collected the data; Kim HJ obtained informed consent from the patient, participated as an assistant in the surgery, and contributed to the data collection; Kim KW contributed to the data analysis and provided conceptualization and supervision; All authors have read and approved the final manuscript.
Informed consent statement: Written consent was obtained from the patient for publication of this anonymized case report.
Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and arrived according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kwan Wook Kim, MD, PhD, Surgeon, Department of Thoracic and Cardiovascular Surgery, CHA Bundang Medical Center, 59, Yatap-ro, Bundang-gu, SeongnamJ-si 13496, South Korea. mujin100km@cha.ac.kr
Received: March 17, 2023 Peer-review started: March 17, 2023 First decision: March 28, 2023 Revised: April 6, 2023 Accepted: May 6, 2023 Article in press: May 6, 2023 Published online: June 6, 2023 Processing time: 77 Days and 5.8 Hours
Abstract
BACKGROUND
Tracheal neoplasms represent less than 0.1% of all malignancies and have no established treatment guidelines. Surgical resection with reconstruction is the primary treatment. This study demonstrates successful treatment of concurrent lung and tracheal tumors using surgical excision and intraoperative photodynamic therapy (PDT), highlighting the effectiveness and safety of this approach.
CASE SUMMARY
A 74-year-old male with a history of smoking and chronic obstructive pulmonary disease was diagnosed with tracheal squamous cell carcinoma and right lower lobe adenocarcinoma. A multidisciplinary team created a treatment plan involving tumor resection and PDT. The tracheal tumor was removed through a tracheal incision and this was followed by intraluminal PDT. The trachea was repaired and a right lower lobectomy was performed. The patient received a second PDT treatment postoperatively and was discharged 10 d after the tracheal surgery, without complications. He then underwent platinum-based chemotherapy for lymphovascular invasion of lung cancer. Three-month postoperative bronchoscopy revealed normal tracheal mucosa with a scar at the resection site and no evidence of tumor recurrence in the trachea or lung.
CONCLUSION
Our case of concurrent tracheal and lung cancers was successfully treated with surgical excision and intraoperative PDT which proved safe and effective in this patient.
Core Tip: This case report presents successful treatment of a rare case of concurrent tracheal and lung cancers in a 74-year-old male patient using surgical excision and intraoperative photodynamic therapy (PDT). This approach proved to be safe and effective, resulting in complete regression of the tracheal tumor. The patient's treatment included a combination of lobectomy, tracheal tumor excision, and intraluminal PDT, demonstrating the potential of this approach in managing such complex cases.
