Xie QJ, Li X, Ni DY, Ji H, Zhao C, Ling XF. Intramural pregnancy after in vitro fertilization and embryo transfer: A case report. World J Clin Cases 2022; 10(9): 2871-2877 [PMID: 35434105 DOI: 10.12998/wjcc.v10.i9.2871]
Corresponding Author of This Article
Xiu-Feng Ling, MD, PhD, Doctor, Department of Reproductive Medicine, Nanjing Maternity and Child Health Care Hospital, Road 123 Tianfeixiang, Mochou, Nanjing 210004, Jiangsu Province, China. lingxiufeng_njfy@163.com
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 26, 2022; 10(9): 2871-2877 Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2871
Intramural pregnancy after in vitro fertilization and embryo transfer: A case report
Qi-Jun Xie, Xin Li, Dan-Yu Ni, Hui Ji, Chun Zhao, Xiu-Feng Ling
Qi-Jun Xie, Xin Li, Dan-Yu Ni, Hui Ji, Chun Zhao, Xiu-Feng Ling, Department of Reproductive Medicine, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu Province, China
Author contributions: Xie QJ was involved in protocol/project development, data collection and management, data analysis and manuscript writing; Li X was involved in project development, images collection and manuscript writing; Ni DY was involved in project development, manuscript review and editing; Ji H, Zhao C and Ling XF was involved in data collection and analysis, manuscript review and editing. Xie QJ and Li X contributed equally to this work.
Supported byNational Natural Science Foundation of China, No. 81971386 and No. 81871210.
Informed consent statement: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the Helsinki declaration. Informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: All authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiu-Feng Ling, MD, PhD, Doctor, Department of Reproductive Medicine, Nanjing Maternity and Child Health Care Hospital, Road 123 Tianfeixiang, Mochou, Nanjing 210004, Jiangsu Province, China. lingxiufeng_njfy@163.com
Received: September 18, 2021 Peer-review started: September 18, 2021 First decision: January 10, 2022 Revised: January 19, 2022 Accepted: February 20, 2022 Article in press: February 20, 2022 Published online: March 26, 2022 Processing time: 185 Days and 9.4 Hours
Abstract
BACKGROUND
Intramural pregnancy is a rare type of ectopic pregnancy, which is diagnosed by transvaginal ultrasound and magnetic resonance imaging. Management strategies vary depending on the site of the pregnancy, the gestational age and the desire to maintain fertility. The incidence of intramural pregnancy in assisted reproductive technology is higher than that in natural pregnancy.
CASE SUMMARY
We present a case of intramural pregnancy after in vitro fertilization and elective single embryo transfer following salpingectomy. The patient was completely asymptomatic and her serum β-human chorionic gonadotropin level increased from 290 mIU/mL to 1759 mIU/mL. Three-dimensional transvaginal ultrasound indicated a heterogeneous echogenic mass arising from the uterine fundus which was surrounded by myometrium and a slender and extremely hypoechoic area stretching to the uterine cavity which was thought to be a fistulous tract. Therefore, we considered a diagnosis of intramural pregnancy and laparoscopic surgery was conducted at 7 wk gestation.
CONCLUSION
Early diagnosis and treatment of intramural pregnancy is significant for maintaining fertility.
Core Tip: We present a case of intramural pregnancy after in vitro fertilization and elective single embryo transfer following bilateral salpingectomy. The patient was diagnosed with intramural pregnancy by transvaginal ultrasound and then underwent laparoscopic surgery at 7 wk’ gestation. The patient recovered well at discharge and her serum β-hCG levels were negative after 4 wk.
