Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 6, 2022; 10(4): 1366-1372
Published online Feb 6, 2022. doi: 10.12998/wjcc.v10.i4.1366
Imaging presentation of biliary adenofibroma: A case report
Shao-Peng Li, Peng Wang, Ke-Xue Deng
Shao-Peng Li, Peng Wang, Ke-Xue Deng, Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (Southern District of Anhui Provincial Hospital), Hefei 230022, Anhui Province, China
Author contributions: All authors conceived the manuscript, supervised the findings of this work; discussed the results; and contributed to the final manuscript; Li SP processed the data; drafted the manuscript; and designed the figures; Wang P contributed to analysis and manuscript preparation and supervise the work; Deng KX was directly responsible for performing the operation, revising the paper; and supervising the work.
Informed consent statement: Informed consent was obtained from the patient for publication of this report and any accompanying images and has been filed with the hospital ethics committee.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ke-Xue Deng, MD, Chief Doctor, Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (Southern District of Anhui Provincial Hospital), No. 1 Tian e hu Road, Shushan District, Hefei 230022, Anhui Province, China. dengkexue-anhui@163.com
Received: August 15, 2021
Peer-review started: August 15, 2021
First decision: November 11, 2021
Revised: November 23, 2021
Accepted: December 22, 2021
Article in press: December 22, 2021
Published online: February 6, 2022
Abstract
BACKGROUND

Biliary adenofibroma (BF) is a rare benign epithelial tumor with the possibility of malignant transformation. Its main pathological feature is a well-defined cystic or honeycomb mass. BF has no specific clinical manifestations or laboratory and imaging findings; thus, it is easily misdiagnosed before surgery. This report describes a case in which biliary cystadenoma was misdiagnosed preoperatively and BF was diagnosed postoperatively. The imaging features, particularly the magnetic resonance imaging (MRI) features, were analyzed and summarized.

CASE SUMMARY

A 68-year-old Chinese man was admitted to our hospital with a 2-mo history of abdominal discomfort. Following admission to our hospital, laboratory examinations showed normal tumor marker concentrations and liver function. Hepatocellular carcinoma was considered after contrast-enhanced ultrasound examination. MRI suggested the possibility of cystadenoma of the bile duct. However, postoperative pathological examination confirmed the diagnosis of BF. No local recurrence was found 1 mo after surgery.

CONCLUSION

Our objective is to highlight the imaging diagnostic value of BF, especially on an MRI enhanced scan with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid.

Keywords: Biliary adenofibroma, Magnetic resonance imaging, Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid, Misdiagnosis, Case report

Core Tip: The imaging presentation of biliary adenofibroma is complex and diverse, and the clinical history and laboratory examination were not specific. In this case, magnetic resonance imaging characteristics of biliary adenofibroma, especially enhanced scan with Gd-EOB-DTPA and an intravoxel incoherent motion diffusion-weighted imaging sequence were valuable.