Jin BC, Ahn AR, Kim SH, Seo SY. Regression of gastric endoscopic submucosal dissection induced polypoid nodular scar after Helicobacter pylori eradication: A case report. World J Clin Cases 2022; 10(34): 12793-12798 [PMID: 36579119 DOI: 10.12998/wjcc.v10.i34.12793]
Corresponding Author of This Article
Seung Young Seo, MD, PhD, Professor, Department of Internal Medicine, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju 54907, South Korea. bear7905@jbnu.ac.kr
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 6, 2022; 10(34): 12793-12798 Published online Dec 6, 2022. doi: 10.12998/wjcc.v10.i34.12793
Regression of gastric endoscopic submucosal dissection induced polypoid nodular scar after Helicobacter pylori eradication: A case report
Byung Chul Jin, Ae Ri Ahn, Seong-Hun Kim, Seung Young Seo
Byung Chul Jin, Seong-Hun Kim, Seung Young Seo, Department of Internal Medicine, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju 54907, South Korea
Ae Ri Ahn, Department of Pathology, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University, Biomedical Research Institute of Jeonbuk National University Hospital, and Research Institute for Endocrine Sciences, Jeonju 56445, South Korea
Author contributions: Jin BC analyzed clinical data and drafted the manuscript; Kim SH, Seo SY advised and reviewed the manuscript; Ahn AR performed the pathologic review.
Informed consent statement: Informed written consent was obtained from the patient regarding the publication of this report and accompanying images.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Seung Young Seo, MD, PhD, Professor, Department of Internal Medicine, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju 54907, South Korea. bear7905@jbnu.ac.kr
Received: October 4, 2022 Peer-review started: October 4, 2022 First decision: October 21, 2022 Revised: November 2, 2022 Accepted: November 8, 2022 Article in press: November 8, 2022 Published online: December 6, 2022 Processing time: 59 Days and 2.8 Hours
Abstract
BACKGROUND
Endoscopic submucosal dissection (ESD) is the treatment of choice for early gastric cancer and premalignant gastric dysplasia. In some cases, ESD induced ulcer heals as a polypoid nodular scar (PNS). These scars may make the physicians raise several clinical implications such as post-ESD neoplastic recurrence.
CASE SUMMARY
We described a case of gastric ESD induced PNS which is regressed after Helicobacter pylori (H. pylori) eradication. A 58-year-old male patient was referred to the outpatient clinic for evaluation and treatment of gastric low-grade dysplasia (LGD). ESD was performed. A PNS was developed at the ESD site. An endoscopic biopsy was done and there was no histological evidence of remnant tumor or recurrence but a hyperplastic mucosal change. The PNS showed increase in size in follow-up endoscopy, and the biopsy specimen demonstrated H. pylori infestation. H. pylori eradication was done and the PNS was regressed.
CONCLUSION
H. pylori eradication is considerable for the regression of PNS if H. pylori infestation is confirmed.
Core Tip: We report a case of gastric endoscopic submucosal dissection induced polypoid nodular scar and regression after Helicobacter pylori eradication.
