Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2022; 10(33): 12200-12207
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12200
Comparison of the prevalence of sarcopenia in geriatric patients in Xining based on three different diagnostic criteria
Shi-Qin Pan, Xiao-Fang Li, Ming-Qin Luo, Yue-Mei Li
Shi-Qin Pan, Xiao-Fang Li, Ming-Qin Luo, Yue-Mei Li, Department of Nuring, Qinghai Provincial People’s Hospital, Xining 810000, Qinghai Province, China
Author contributions: Pan SQ and Li XF designed and performed the research; Luo MQ and Li YM contributed new reagents and analytic tools; Pan SQ analyzed the data; Pan SQ wrote the paper.
Supported by the Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, No. 2018PT33001.
Institutional review board statement: This study was approved by the ethics committee of Qinghai Provincial People’s Hospital. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yue-Mei Li, PhD, Chief Nurse, Department of Nursing, Qinghai Provincial People’s Hospital, No. 2 Gonghe Road, Xining 810000, Qinghai Province, China. lym64913@126.com
Received: July 22, 2022
Peer-review started: July 22, 2022
First decision: September 25, 2022
Revised: October 18, 2022
Accepted: October 31, 2022
Article in press: October 31, 2022
Published online: November 26, 2022
Processing time: 117 Days and 24 Hours
Abstract
BACKGROUND

Sarcopenia is an age-related decline in skeletal muscle mass, which depends on an assessment of muscle strength and muscle mass. The diagnostic definition of sarcopenia varies by region.

AIM

To determine the optimal diagnostic criteria for sarcopenia in a plateau population. Cut off values for the components of diagnostic algorithms for sarcopenia in plateau populations should consider altitude.

METHODS

One hundred and fifty subjects aged > 60 years attending a tertiary comprehensive hospital in the city of Xining (elevation: 2260 m) between October and December 2018 were enrolled. Handgrip strength, muscle mass, and physical performance were measured. Sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia (AWGS) 2019 criteria, Beijing criteria, and Lasha criteria.

RESULTS

Across diagnostic criteria, there were significant differences in the prevalence of sarcopenia in the overall population and stratified by gender. The prevalence of sarcopenia measured by the AWGS 2019 or Lasha criteria was significantly higher in female compared to male subjects. In males, the prevalence of sarcopenia measured by the Beijing criteria was significantly higher in subjects who identified as Han compared to Minority. In females, there were no significant differences in the prevalence of sarcopenia by ethnicity according to any criteria.

CONCLUSION

The Lasha criteria provided a lower prevalence of sarcopenia (males, 8.7%; females, 22.41%; overall, 14%) and were able to differentiate between males and females. The Lasha criteria are likely most appropriate for detection of sarcopenia in this plateau population. We recommend the Lasha criteria for detection of sarcopenia in Xining.

Keywords: Ethnic; Diagnostic criteria; Sarcopenia; Prevalence; Plateau

Core Tip: Cutoff values for the components of diagnostic algorithms for sarcopenia in plateau populations should consider altitude. We found the Lasha criteria provided a lower prevalence of sarcopenia (males, 8.7%; females, 22.41%; overall, 14%) and were able to differentiate between males and females. The Lasha criteria are likely most appropriate for detection of sarcopenia in this plateau population. We recommend the Lasha criteria for detection of sarcopenia in Xining.