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World J Clin Cases. Nov 26, 2022; 10(33): 12066-12076
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12066
Review of risk factors, clinical manifestations, rapid diagnosis, and emergency treatment of neonatal perioperative pneumothorax
Xu Zhang, Ning Zhang, Yue-Yi Ren
Xu Zhang, Yue-Yi Ren, Department of Heart Center, Women's and Children's Hospital Affiliated to Qingdao University, Qingdao 266034, Shandong Province, China
Ning Zhang, Department of Clinical Laboratory, Women's and Children's Hospital Affiliated to Qingdao University, Qingdao 266034, Shandong Province, China
Author contributions: Zhang X and Ren YY designed this review; Zhang X and Zhang N wrote the review; Ren YY revised the review; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yue-Yi Ren, MD, Associate Chief Physician, Associate Professor, Department of Heart Center, Women's and Children's Hospital Affiliated to Qingdao University, No. 217 Liaoyang West Road, Shibei District, Qingdao 266034, Shandong Province, China. xxgmz1173@126.com
Received: July 16, 2022
Peer-review started: July 16, 2022
First decision: September 5, 2022
Revised: September 16, 2022
Accepted: October 19, 2022
Article in press: October 19, 2022
Published online: November 26, 2022
Processing time: 129 Days and 9.8 Hours
Abstract

Perioperative neonatal pneumothorax (NP) is rare but very fatal. Most of the surgeries and treatments in the neonatal period are time-limited or emergent, and there are often some risk factors for pneumothorax before surgery. Physicians, surgeons and anesthesiologists need to identify possible risk factors for pneumothorax before surgery in preterm babies, patients receiving mechanical ventilation and those with underlying lung disease. The clinical presentation of NP is nonspecific, and patients may rapidly develop life-threatening complications if not promptly diagnosed and managed. This review highlights recent progress in the identification of risk factors, clinical manifestations, diagnosis and management of NP during the perioperative period.

Keywords: Neonatal; Perioperative; Pneumothorax; Risk factors; Clinical manifestations; Diagnosis; Management

Core Tip: Perioperative neonatal pneumothorax (NP) is rare but very fatal. The clinical presentation of NP is nonspecific, and patients may rapidly develop life-threatening complications if not promptly diagnosed and managed. This review highlights recent progress in the identification of risk factors, clinical manifestations, diagnosis and management of NP during the perioperative period.