Lakkasani S, Seth D, Khokhar I, Touza M, Dacosta TJ. Concise review on short bowel syndrome: Etiology, pathophysiology, and management. World J Clin Cases 2022; 10(31): 11273-11282 [PMID: 36387822 DOI: 10.12998/wjcc.v10.i31.11273]
Corresponding Author of This Article
Saraswathi Lakkasani, MD, Academic Fellow, Gastroenterology and Hepatology, Saint Michael's Medical Center in Affiliation with New York Medical College, 111 Central Ave, Newark, NJ 07102, United States. dr.saraswathi.l@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Saraswathi Lakkasani, Theodore Jr Dacosta, Gastroenterology and Hepatology, Saint Michael’s Medical Center in Affiliation with New York Medical College, Newark, NJ 07102, United States
Deeksha Seth, Gastroenterology, Chandan Institute of Liver and Biliary Sciences, Lucknow 226001, India
Imran Khokhar, Medicine, Suburban Medical Center, Norristown, PA 19401, United States
Masara Touza, Medicine, Saint Michael’s Medical Center in Affiliation with New York Medical College, Newark, NJ 07102, United States
Author contributions: Lakkasani S contributed to the literature search, manuscript writing, editing, and review; Seth D contributed to the manuscript writing and editing; Khokhar I contributed to the manuscript writing; Touza M contributed to the manuscript writing and editing; Dacosta T contributed to reviewing the article.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Saraswathi Lakkasani, MD, Academic Fellow, Gastroenterology and Hepatology, Saint Michael's Medical Center in Affiliation with New York Medical College, 111 Central Ave, Newark, NJ 07102, United States. dr.saraswathi.l@gmail.com
Received: July 5, 2022 Peer-review started: July 5, 2022 First decision: July 31, 2022 Revised: August 12, 2022 Accepted: September 20, 2022 Article in press: September 20, 2022 Published online: November 6, 2022 Processing time: 113 Days and 7.7 Hours
Abstract
Adults have approximately 20 feet of small intestine, which is the primary site for absorbing essential nutrients and water. Resection of the intestine for any medical reason may result in short bowel syndrome (SBS), leading to loss of major absorptive surface area and resulting in various malabsorption and motility disorders. The mainstay of treatment is personalized close dietary management. Here we present SBS with its pathophysiology and different nutritional management options available. The central perspective of this paper is to provide a concise review of SBS and the treatment options available, along with how proper nutrition can solve major dietary issues in SBS and help patients recover faster.
Core Tip: This is a very informative review about the etiology, pathophysiology, and management of short bowel syndrome (SBS) with newer treatment options based on extensive literature review and expert opinion. The review details significant stages in short bowel syndrome, especially the process of intestinal adaptation. This paper provides detailed information regarding the preferred nutritional management of patients with different types of SBS during different stages of the disease.
