He Y, Ji H, Xie JC, Zhou L. Coronary artery aneurysms caused by Kawasaki disease in an adult: A case report and literature review. World J Clin Cases 2022; 10(28): 10266-10272 [PMID: 36246810 DOI: 10.12998/wjcc.v10.i28.10266]
Corresponding Author of This Article
Liang Zhou, MM, Chief Physician, Department of Cardiology, Hangzhou First People's Hospital Affiliated to Zhejiang University School of Medicine, No. 261 Huansha Road, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. zl_hzsy@163.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2022; 10(28): 10266-10272 Published online Oct 6, 2022. doi: 10.12998/wjcc.v10.i28.10266
Coronary artery aneurysms caused by Kawasaki disease in an adult: A case report and literature review
Ying He, Hao Ji, Jian-Chang Xie, Liang Zhou
Ying He, Hao Ji, The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Jian-Chang Xie, Liang Zhou, Department of Cardiology, Hangzhou First People's Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Author contributions: The main contributor is He Y; He Y wrote the manuscript; Ji H and Xie JC were the treating physicians and were responsible for revising the manuscript; Zhou L provided assistance during the diagnosis and treatment; Zhou L performed surgery, and Ji H helped analyze the imaging data; all authors read and endorsed the final draft.
Supported byScientific Research Fund of Zhejiang Provincial Education Department, No. Y202145971.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Liang Zhou, MM, Chief Physician, Department of Cardiology, Hangzhou First People's Hospital Affiliated to Zhejiang University School of Medicine, No. 261 Huansha Road, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. zl_hzsy@163.com
Received: May 3, 2022 Peer-review started: May 3, 2022 First decision: June 7, 2022 Revised: June 13, 2022 Accepted: August 25, 2022 Article in press: August 25, 2022 Published online: October 6, 2022 Processing time: 146 Days and 23.5 Hours
Abstract
BACKGROUND
Kawasaki disease (KD) is a self-limiting febrile illness and an acute vasculitis with an unknown origin. It predominantly affects children aged < 5 years. KD is the common cause of acquired heart disease in children. We here report a case of KD in an asymptomatic young female patient diagnosed with multiple coronary aneurysms with calcification.
CASE SUMMARY
A 29-year-old female patient admitted to Hangzhou First People's Hospital with coronary artery abnormality identified for 1 wk. The patient was asymptomatic; however, chest computed tomography occasionally revealed strip-like dense shadows in the coronal sulcus. After coronary angiography and Doppler echocardiography, the final diagnosis was coronary artery aneurysms (CAAs) caused by KD. Although the patient was asymptomatic with no history of KD in childhood, the definitive diagnosis was CAAs caused by KD. The patient was administered anticoagulant, and surgical treatment was recommended.
CONCLUSION
KD potentially causes CAAs in 25% of untreated cases, primarily occurring in the proximal portions of the coronary arteries.
Core Tip: Kawasaki disease (KD) is the self-limited febrile illness and predominantly affects children < 5 years of age. Here, we report a case of KD in a young girl with coronary artery aneurysms, but with no symptoms. Coronary artery aneurysms occur primarily in the proximal portions of the major coronary arteries in KD, which may result in myocardial infarction. Patients should be diagnosed and treated immediately to obtain a favorable prognosis.
