Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2022; 10(25): 9132-9141
Published online Sep 6, 2022. doi: 10.12998/wjcc.v10.i25.9132
Chondrosarcoma of the toe: A case report and literature review
Li-Bo Zhou, He-Cheng Zhang, Zai-Gang Dong, Chao-Chao Wang
Li-Bo Zhou, He-Cheng Zhang, Zai-Gang Dong, Graduate School, Qinghai University, Xining 810016, Qinghai Province, China
Chao-Chao Wang, Department of Bone and Joint Surgery, the Affiliated Hospital of Qinghai University, Xining 810012, Qinghai Province, China
Author contributions: Zhou LB and Wang CC designed the study; Zhang HC collected the data; Zhou LB drafted the manuscript; Wang CC analyzed and interpreted the imaging and pathology results; Dong ZG performed patient follow-up; and All authors have read and approved the manuscript.
Informed consent statement: The patient agreed to publish her medical records and images. Written informed consent was obtained from the patient.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chao-Chao Wang, MD, Attending Doctor, Department of Bone and Joint Surgery, the Affiliated Hospital of Qinghai University, No. 29 Tongren Road, Chengxi District, Xining 810012, Qinghai Province, China. 490209397@qq.com
Received: April 26, 2022
Peer-review started: April 26, 2022
First decision: June 16, 2022
Revised: June 25, 2022
Accepted: July 22, 2022
Article in press: July 22, 2022
Published online: September 6, 2022
Processing time: 122 Days and 5.1 Hours
Abstract
BACKGROUND

Chondrosarcoma of the foot is a rare malignant bone tumour, and it is even rarer when it originates in a toe bone. Surgical excision is the only effective treatment. The osteolytic destruction of the tumour severely affects limb function and carries the risk of distant metastasis. Most such tumours are removed surgically to minimize local recurrence and distant metastases, maximize limb function, and prolong the patient's tumour-free survival time. The main objective of this article is to present the case of a chondrosarcoma that invaded the first phalanx of the left foot and formed a large phalangeal mass with osteolytic destruction of the distal bone.

CASE SUMMARY

A 74-year-old man suffered from swelling of his left toe for six months, with pain and swelling for two months. Computed tomography and magnetic resonance imaging showed that the tumour on the first phalanx of the left foot was approximately 54.9 mm × 44.6 mm, surrounded by a significant soft tissue signal mass, with osteolytic destruction of the distal phalanx and a speckled bone-like high-density shadow within it.

CONCLUSION

Chondrosarcoma occurring in a toe bone is extremely rare. In this case, extensive surgical resection of the large low-grade chondrosarcoma, which showed osteolytic destruction and invaded the distal metatarsal bone, was safe and effective.

Keywords: Chondrosarcoma, Phalanges tumour, Diagnosis, Surgery, Case report

Core Tip: The main objective of this article is to present a case of chondrosarcoma that invaded the first phalanx of the left foot and formed a sizeable phalangeal mass with osteolytic destruction of the distal bone. Chondrosarcoma originating in a toe bone has only been sporadically reported, and this case report will help clinicians better understand this rare lesion.