Wang Y, Ge ZJ, Han C. Intranasal sufentanil combined with intranasal dexmedetomidine: A promising method for non-anesthesiologist sedation during endoscopic ultrasonography . World J Clin Cases 2022; 10(23): 8428-8431 [PMID: 36159524 DOI: 10.12998/wjcc.v10.i23.8428]
Corresponding Author of This Article
Chao Han, MD, Assistant Professor, Department of Anesthesiology, The Affiliated Yixing Hospital of Jiangsu University, No. 75 Tongzhenguan Road, Yixing 214200, Jiangsu Province, China. staff940@yxph.com
Research Domain of This Article
Anesthesiology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Aug 16, 2022; 10(23): 8428-8431 Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8428
Intranasal sufentanil combined with intranasal dexmedetomidine: A promising method for non-anesthesiologist sedation during endoscopic ultrasonography
Yong Wang, Zhi-Jun Ge, Chao Han
Yong Wang, Chao Han, Department of Anesthesiology, The Affiliated Yixing Hospital of Jiangsu University, Yixing 214200, Jiangsu Province, China
Yong Wang, Zhi-Jun Ge, School of Medical, Jiangsu University, Zhenjiang 212013, Jiangsu Province, China
Author contributions: Wang Y and Ge ZJ designed and performed the research; Han C wrote and revised the letter.
Conflict-of-interest statement: All authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chao Han, MD, Assistant Professor, Department of Anesthesiology, The Affiliated Yixing Hospital of Jiangsu University, No. 75 Tongzhenguan Road, Yixing 214200, Jiangsu Province, China. staff940@yxph.com
Received: March 30, 2022 Peer-review started: March 30, 2022 First decision: June 19, 2022 Revised: June 24, 2022 Accepted: July 16, 2022 Article in press: July 16, 2022 Published online: August 16, 2022 Processing time: 124 Days and 0.5 Hours
Abstract
Intranasal sufentanil combined with intranasal dexmedetomidine exhibited an estimated sedation success probability as high as 94.9%, higher satisfaction scores, and only minor adverse events during endoscopic ultrasonography (EUS). This is a promising method for EUS sedation that does not require the presence of an anesthesiologist.
Core Tip: Endoscopic ultrasonography (EUS) requires moderate-to-deep sedation due to a prolonged procedure time and a larger and stiffer probe. Propofol-based sedation is the predominant method used in such cases for rapid onset and improved sedation with rapid full recovery. However, there are still restrictions regarding the administration of propofol in the absence of an anesthesiologist. The combination of intranasal sufentanil and intranasal dexmedetomidine exhibited an estimated sedation success probability, higher satisfaction scores, and minor adverse events, thus highlighting a promising method for EUS sedation in the absence of an anesthesiologist.
