Liu CC, Huang WP, Gao JB. Primary clear cell sarcoma of soft tissue in the posterior cervical spine invading the medulla oblongata: A case report. World J Clin Cases 2022; 10(21): 7571-7576 [PMID: 36158008 DOI: 10.12998/wjcc.v10.i21.7571]
Corresponding Author of This Article
Jian-Bo Gao, PhD, Academic Research, Chairman, Chief Doctor, Instructor, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Zhengzhou 450052, Henan Province, China. jianbogaochina@163.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 26, 2022; 10(21): 7571-7576 Published online Jul 26, 2022. doi: 10.12998/wjcc.v10.i21.7571
Primary clear cell sarcoma of soft tissue in the posterior cervical spine invading the medulla oblongata: A case report
Chen-Chen Liu, Wen-Peng Huang, Jian-Bo Gao
Chen-Chen Liu, Wen-Peng Huang, Jian-Bo Gao, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Author contributions: Liu CC wrote the article; Huang WP designed the research study; Gao JB is the corresponding author; and all authors have read and approved the final manuscript.
Informed consent statement: The study was approved by the Institutional Review Board of the First Affiliated Hospital of Zhengzhou University. Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Bo Gao, PhD, Academic Research, Chairman, Chief Doctor, Instructor, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Zhengzhou 450052, Henan Province, China. jianbogaochina@163.com
Received: February 11, 2022 Peer-review started: February 11, 2022 First decision: March 23, 2022 Revised: April 2, 2022 Accepted: May 28, 2022 Article in press: May 28, 2022 Published online: July 26, 2022 Processing time: 149 Days and 17.2 Hours
Abstract
BACKGROUND
Clear cell sarcoma (CCS) is a rare and highly malignant soft tissue tumor, usually occurring in the deep soft tissues of the distal tendons and aponeurosis of the extremities, especially the feet and knees. CCS originating in the head and neck is extremely rare. The clinical manifestations of CCS in the head and neck are not typical, and the imaging manifestations have certain characteristics, but the diagnosis still depends on pathological examination and genetic testing.
CASE SUMMARY
A 33-year-old male patient had paroxysmal headache for more than 4 years, accompanied by nausea and vomiting, which could be relieved after rest. Computed tomography angiography showed a left paraspinal soft tissue mass. Contrast-enhanced imaging showed obvious uneven enhancement with adjacent bone lytic destruction. Magnetic resonance imaging examination showed isosignal on T1-weighted images, slightly high signal on T2-weighted images (T2WI), high signal on Tirm fat suppression sequence, significantly high signal on diffusion weighted imaging, and obvious and uneven enhancement. The lesion invaded the anterior medulla oblongata through the left atlantoaxial foramen and compressed the cervical spinal cord on T2WI. Primary CCS of soft tissue was diagnosed by pathology and genetic examination.
CONCLUSION
CCS should be considered in the differential diagnosis of soft tissue tumors of the head and neck, and their diagnosis depends on pathological examination and genetic testing.
Core Tip: Clear cell sarcoma (CCS) is a rare and highly malignant soft tissue tumor, usually occurring in the deep soft tissues of the distal tendons and aponeurosis of the extremities. CCS originating in the head and neck is extremely rare and usually presents as a painless growth mass. In this case, the lesion was located in the head and neck and presented as episodic headache. The lesion was perforated and involved the medulla oblongata. Differential diagnosis of malignant soft tissue tumors of the head and neck should consider CCS based on pathological and genetic tests.
