Xie GY, Zhu HB, Jin Y, Li BZ, Yu YQ, Li JT. Solitary fibrous tumor of the liver: A case report and review of the literature. World J Clin Cases 2022; 10(20): 7097-7104 [PMID: 36051139 DOI: 10.12998/wjcc.v10.i20.7097]
Corresponding Author of This Article
Jiang-Tao Li, FACS, MD, Director, Surgeon, Department of Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, No.88, Jiefang Road, Hangzhou 310009, Zhejiang Province, China. zrljt@zju.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Guang-Yuan Xie, Huan-Bing Zhu, Yun Jin, Yuan-Quan Yu, Jiang-Tao Li, Department of Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Bai-Zhou Li, Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, HangZhou 310000, Zhejiang Province, China
Author contributions: Xie GY and Zhu HB performed the study, reviewed the literature and contributed to manuscript drafting; Li JT, Jin Y, and Yu YY were the patient’s physicians in charge and contributed to manuscript drafting; Li BZ performed the histological analyses and interpretation; Li JT edited the manuscript and critically revised the draft; All authors issued final approval for the version to be submitted.
Supported byNational Natural Science Foundation of China, No.81770614.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jiang-Tao Li, FACS, MD, Director, Surgeon, Department of Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, No.88, Jiefang Road, Hangzhou 310009, Zhejiang Province, China. zrljt@zju.edu.cn
Received: December 17, 2021 Peer-review started: December 17, 2021 First decision: January 26, 2022 Revised: January 30, 2022 Accepted: May 22, 2022 Article in press: May 22, 2022 Published online: July 16, 2022 Processing time: 199 Days and 12.3 Hours
Abstract
BACKGROUND
Hepatic solitary fibrous tumor (SFT) is a rare neoplasm. Up to now, only 90 cases have been reported in the English language literature. This report describes a case of SFT of the liver misdiagnosed as hepatocellular carcinoma.
CASE SUMMARY
A 42-year-old male had a two-year history of a gradually enlarging intrahepatic nodule. The preoperative imaging revealed a mass with a size of 2.7 cm × 2.3 cm located in the segment IV of the liver. The patient was subjected to the resection of the segment IV, such as the medial segment of the left lobe of the liver. The histological examination of the mass showed various spindled cells irregularly arranged in the stroma. The immunohistochemistry of this mass revealed a positive staining for CD34 and STAT6. The history of intracranial tumor and postoperative pathological results led to the diagnosis of SFT of the liver (SFTL) due to a metastasis from the brain.
CONCLUSION
SFTL is an uncommon mesenchymal neoplasm that can be easily overlooked or misdiagnosed. The best treatment choice is the complete surgical resection of the mass. A regular follow-up after the surgery should be performed due to the poor prognosis of metastatic or recurrent SFT.
Core Tip: This article describes a rare case of liver mesenchymal neoplasm preoperatively misdiagnosed as hepatocellular carcinoma. The postoperative pathological examination confirmed the diagnosis of solitary fibrous tumor. A metastatic lesion was primarily considered due to the history of intracranial hemangiopericytoma. Its radiological features, diagnosis, and treatment strategies are also discussed.
