Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.7097
Peer-review started: December 17, 2021
First decision: January 26, 2022
Revised: January 30, 2022
Accepted: May 22, 2022
Article in press: May 22, 2022
Published online: July 16, 2022
Processing time: 199 Days and 12.3 Hours
Hepatic solitary fibrous tumor (SFT) is a rare neoplasm. Up to now, only 90 cases have been reported in the English language literature. This report describes a case of SFT of the liver misdiagnosed as hepatocellular carcinoma.
A 42-year-old male had a two-year history of a gradually enlarging intrahepatic nodule. The preoperative imaging revealed a mass with a size of 2.7 cm × 2.3 cm located in the segment IV of the liver. The patient was subjected to the resection of the segment IV, such as the medial segment of the left lobe of the liver. The histological examination of the mass showed various spindled cells irregularly arranged in the stroma. The immunohistochemistry of this mass revealed a positive staining for CD34 and STAT6. The history of intracranial tumor and postoperative pathological results led to the diagnosis of SFT of the liver (SFTL) due to a metastasis from the brain.
SFTL is an uncommon mesenchymal neoplasm that can be easily overlooked or misdiagnosed. The best treatment choice is the complete surgical resection of the mass. A regular follow-up after the surgery should be performed due to the poor prognosis of metastatic or recurrent SFT.
Core Tip: This article describes a rare case of liver mesenchymal neoplasm preoperatively misdiagnosed as hepatocellular carcinoma. The postoperative pathological examination confirmed the diagnosis of solitary fibrous tumor. A metastatic lesion was primarily considered due to the history of intracranial hemangiopericytoma. Its radiological features, diagnosis, and treatment strategies are also discussed.