Case Control Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2022; 10(20): 6794-6802
Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.6794
Urinary and sexual function changes in benign prostatic hyperplasia patients before and after transurethral columnar balloon dilatation of the prostate
Dong-Peng Zhang, Zheng-Bo Pan, Hai-Tao Zhang
Dong-Peng Zhang, Department of Urology, Tianjin Hospital, Tianjin 300211, China
Zheng-Bo Pan, Hai-Tao Zhang, Department of Urology, Taizhou Municipal Hospital, Taizhou 318000, Zhejiang Province, China
Author contributions: Zhang DP and Zhang HT designed the research study; Zhang DP performed the research; Pan ZB contributed new reagents and analytic tools; Zhang DP analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Taizhou Municipal Hospital Institutional Review Board (Approval No. 119).
Informed consent statement: All patients provided informed consent.
Conflict-of-interest statement: None conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zheng-Bo Pan, MHSc, Attending Doctor, Department of Urology, Taizhou Municipal Hospital, No. 381 Zhongshan East Road, Jiaojiang District, Taizhou 318000, Zhejiang Province, China. pzbzt008501@163.com
Received: December 18, 2021
Peer-review started: December 18, 2021
First decision: January 25, 2022
Revised: February 16, 2022
Accepted: March 16, 2022
Article in press: March 16, 2022
Published online: July 16, 2022
Processing time: 198 Days and 13.8 Hours
Abstract
BACKGROUND

Transurethral columnar balloon dilatation of the prostate (TUCBDP) is a new surgical treatment, but its efficacy remains controversial because of limited clinical application.

AIM

To investigate the clinical effect of TUCBDP for benign prostatic hyperplasia (BPH).

METHODS

Overall, 140 patients with BPH who underwent surgical treatment were included in the study. A random number table was used to divide the participants into study and control groups (n = 70 per group). The study group underwent TUCBDP. The prostate resection surgical time, intraoperative blood loss, bladder irrigation time, catheter indwelling time, length of hospital stay, International Prostate Symptom Score (IPSS), maximum urine flow rate (Qmax), residual urine volume (RUV), changes in the International Erectile Function Score (IIEF-5) score, serum prostate-specific antigen (PSA), quality of life (QOL) score, and surgical complications were compared in both groups.

RESULTS

The operation time, intraoperative blood loss volume, bladder flushing time, urinary catheter indwelling time, and length of hospital stay were significantly lower in the study group than in the control group (P < 0.05). There were no significant differences in the IPSS, Qmax, and RUV measurements between the study and control groups (P > 0.05). However, at 3 mo post-surgery, the IPSS and RUV measurements were both lower (P < 0.05) and Qmax values were higher (P < 0.05) compared to the pre-surgery results in both groups. The IIEF-5 scores before and 3 mo after surgery were not significantly different between the study and control groups (P > 0.05). At 1 mo after surgery, the IIEF-5 score was higher in the study group than in the control group (P < 0.05). The serum PSA levels and QOL scores before treatment and at 1 and 3 mo after treatment were not significantly different between the study and control groups (P > 0.05). However, lower serum PSA levels and QOL scores were observed after 1 and 3 mo of treatment compared to pre-treatment levels in the study group (P < 0.05). The surgical complication rate of the study group (4.29%) was lower than that of the control group (12.86%; P < 0.05).

CONCLUSION

TUCBDP for BPH and transurethral resection of the prostate can achieve better results, but the former method is associated with less surgical trauma.

Keywords: Benign prostatic hyperplasia; Quality of life; Lower urinary tract symptoms; Sexual dysfunction; Transurethral columnar balloon dilatation of the prostate; Transurethral resection of the prostate

Core Tip: By comparing the clinical effects of transurethral columnar balloon dilatation of the prostate (TUCBDP) to the gold standard transurethral resection of the prostate in patients with benign prostatic hyperplasia, it was observed that although both procedures can achieve similar therapeutic effects, TUCBDP offers the additional benefits of less surgical trauma, improved recovery, and fewer surgery-associated complications.