Chen ZH, Guo HQ, Chen JJ, Zhang Y, Zhao L. Imaging-based diagnosis for extraskeletal Ewing sarcoma in pediatrics: A case report . World J Clin Cases 2022; 10(19): 6595-6601 [PMID: 35979293 DOI: 10.12998/wjcc.v10.i19.6595]
Corresponding Author of This Article
Li Zhao, MD, Deputy Director, Department of Radiology, Shaoxing People's Hospital, No. 568 Zhongxin North Street, Shaoxing, Shaoxing 312000, Zhejiang Province, China. 269972605@qq.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 6, 2022; 10(19): 6595-6601 Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6595
Imaging-based diagnosis for extraskeletal Ewing sarcoma in pediatrics: A case report
Zhi-Hui Chen, He-Qing Guo, Jing-Jing Chen, Ying Zhang, Li Zhao
Zhi-Hui Chen, Medical Ultrasound, Affiliated Lishui Hospital of Zhejiang University, The Fifth Affiliated Hospital of Wenzhou Medical University, The Central Hospital of Zhejiang Lishui, Lishui 323000, Zhejiang Province, China
He-Qing Guo, Medical Ultrasound, Women and Children Hospital of Shaoxing, Shaoxing 312000, Zhejiang Province, China
Jing-Jing Chen, Electrocardiogram Room, Cixi integrated Traditional Chinese and Western Medicine Medical, Health Group Cixi Hospital of Traditional Chinese Medicine, Cixi 315300, Zhejiang Province, China
Ying Zhang, Medical Ultrasound, Ningbo Medical Center Lihuili Hospital, Ningbo 315040, Zhejiang Province, China
Li Zhao, Department of Radiology, Shaoxing People's Hospital, Shaoxing 312000, Zhejiang Province, China
Author contributions: Zhao L designed the research; Chen ZH wrote the paper; Guo HQ, Chen JJ and Zhang Y provided and analyzed the images; all authors have read and approved the final version of the manuscript.
Informed consent statement: Informed consent statement was waived.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016) and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li Zhao, MD, Deputy Director, Department of Radiology, Shaoxing People's Hospital, No. 568 Zhongxin North Street, Shaoxing, Shaoxing 312000, Zhejiang Province, China. 269972605@qq.com
Received: November 27, 2021 Peer-review started: November 27, 2021 First decision: January 12, 2022 Revised: January 24, 2021 Accepted: May 16, 2022 Article in press: May 16, 2021 Published online: July 6, 2022 Processing time: 209 Days and 5 Hours
Abstract
BACKGROUND
Extraskeletal Ewing sarcoma (EES) is a member of the Ewing sarcoma family of tumors which is pathologically known as a small, round, blue cell tumor involving bone and soft tissue. The prevalence of EES is only 15%-25% of all Ewing sarcoma and EES often occurs in patients aged from 20-mo-old to 30-years-old resulting in an unfavorable prognosis.
CASE SUMMARY
The present case report described a 7-year-old patient with a palpable EES mass of 33 mm × 27 mm × 28 mm in the deep neck with symptoms of persistent dyspnea over the past 5 mo. After laboratory examinations, abnormal physiological and biochemical indicators were not found. Ultrasound images presented the mass to be complex, solid and fluid-filled with circumscribed margins and posterior acoustic enhancement. The mass also presented with partial internal vascularity. The contrast-enhanced magnetic resonance imaging scan illustrated the outstanding enhancement with fast perfusion mode in the early arterial phase.
CONCLUSION
Our study suggested that a quick-growing mass in the pediatric patient is possibly a malignant tumor whether the mass has well-defined margins or not.
Core Tip: The depth, growth rate and solitary location are valuable indicators for the pre-operative diagnosis of Extraskeletal Ewing sarcoma (EES). Meanwhile, the serpentine-like vascularity was present inside EES, accompanied by the outstanding enhancement with fast perfusion mode in the early arterial phase on the contrast-enhanced magnetic resonance imaging. Multimodal imaging is helpful for clarifying the tumor stage and follow-up.
