Chen YL, Zhou J, Yu HL. Esophageal granular cell tumor: A case report. World J Clin Cases 2022; 10(19): 6543-6547 [PMID: 35979306 DOI: 10.12998/wjcc.v10.i19.6543]
Corresponding Author of This Article
Hui-Ling Yu, MA, Doctor, Department of Gastroenterology, the Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Baoding 071000, Hebei Province, China. 2290165473@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 6, 2022; 10(19): 6543-6547 Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6543
Esophageal granular cell tumor: A case report
Ya-Lan Chen, Jing Zhou, Hui-Ling Yu
Ya-Lan Chen, Hui-Ling Yu, Department of Gastroenterology, the Affiliated Hospital of Hebei University, Baoding 071000, Hebei Province, China
Jing Zhou, Department of Gastroenterology, Wangdu County Hospital, Baoding 071000, Hebei Province, China
Author contributions: Chen YL wrote the initial draft and drafted the data and figures; Yu HL revised the draft; Zhou J provided clinical supervision and edited the manuscript; All authors approved the final version of the manuscript.
Informed consent statement: The study participant provided informed written consent prior to the study.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
CARE Checklist (2016) statement: The article is consistent for CARE Checklist (2016) statemen.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Ling Yu, MA, Doctor, Department of Gastroenterology, the Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Baoding 071000, Hebei Province, China. 2290165473@qq.com
Received: September 14, 2021 Peer-review started: September 14, 2021 First decision: September 29, 2021 Revised: November 2, 2021 Accepted: May 5, 2022 Article in press: May 5, 2022 Published online: July 6, 2022 Processing time: 283 Days and 4.2 Hours
Abstract
BACKGROUND
Esophageal granular cell tumor (eGCT) is a relatively rare, usually benign neoplasm of the neuroectoderm. It is derived from Schwann cells. Clinical symptoms of this disease are non-specific. However, the most common presenting symptom is dysphagia, which is mostly misdiagnosed as esophageal polyps under gastroscopy, yet it has a 2% chance of forming cancers. We report the case of a 52-year-old woman with solitary eGCT, then analysed retrospectivelyanalyze the clinical features and elucidate on the reduction of misdiagnosis and missed diagnosis.
CASE SUMMARY
A 52-year-old woman was diagnosed with “esophageal granulossoma” after esophagoscopy, which was mistaken for eGCT.
CONCLUSION
eGCT diagnosis depends on characteristic pathomorphologies and detection of the S-100 protein. Endoscopic mucosal resection is the preferred therapeutic method.
Core Tip: Esophageal granular cell tumor is a relatively rare, usually benign neoplasm of the neuroectoderm. It is derived from Schwann cells. Clinical symptoms of this disease are non-specific. However, the most common presenting symptom is dysphagia, which is mostly misdiagnosed as esophageal polyps under gastroscopy, yet it has a 2% chance of forming cancers. In this report, clinical features are analyzed to facilitate the reduction of misdiagnosis and missed diagnosis.
