Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2022; 10(17): 5770-5775
Published online Jun 16, 2022. doi: 10.12998/wjcc.v10.i17.5770
Neuroendocrine tumour of the descending part of the duodenum complicated with schwannoma: A case report
Lu Zhang, Chi Zhang, Shu-Yan Feng, Pan-Pan Ma, Shuo Zhang, Qian-Qian Wang
Lu Zhang, Chi Zhang, Shu-Yan Feng, Pan-Pan Ma, Shuo Zhang, Qian-Qian Wang, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China
Author contributions: Zhang L and Zhang S were involved in the conception of the study; Zhang L and Zhang C were involved in writing the article; Zhang L, Ma PP, Feng SY, Wang QQ and Zhang S critically revised the manuscript; all authors read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82074214; and the Research Fund Project of Zhejiang Chinese Medical University, No. 2019ZY02.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qian-Qian Wang, Doctor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang Chinese Medical University, No. 54 Youdian Road, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. w18072348608@163.com
Received: November 21, 2021
Peer-review started: November 21, 2021
First decision: December 26, 2021
Revised: January 6, 2022
Accepted: April 4, 2022
Article in press: April 4, 2022
Published online: June 16, 2022
Processing time: 200 Days and 2 Hours
Abstract
BACKGROUND

No known case of neuroendocrine tumour (NET) with schwannoma has been reported.

CASE SUMMARY

A 63-year-old female presented to our hospital with nausea and vomiting. Upper gastrointestinal endoscopy revealed a mass in the descending part of the duodenum. Using ultrasound gastroscopy, we found that the tumour originated from the submucosa and showed low echo. We removed the tumour by electrocoagulation and sent it for pathological biopsy.

CONCLUSION

Immunohistochemical results showed that the mass was a rare NET with neurilemmoma.

Keywords: Neuroendocrine tumour; Schwannoma; Duodenum; Endoscopy; Immunohistochemistry; Trap with current; Case report

Core Tip: Neuroendocrine tumours (NETs) and schwannomas of the duodenum are quite rare and few clinical cases have been reported. To the best of our knowledge, this is the first publication of a NET of descending duodenum complicated with schwannoma. Through a review of relevant literature, we can deepen the understanding of this type of tumour.