Published online May 6, 2022. doi: 10.12998/wjcc.v10.i13.4314
Peer-review started: December 6, 2021
First decision: January 25, 2022
Revised: January 30, 2022
Accepted: March 6, 2022
Article in press: March 6, 2022
Published online: May 6, 2022
Processing time: 144 Days and 19.2 Hours
The brain is the most important organ to maintain life. However, the amount of brain tissue required for maintaining life in humans has not been previously reported.
A 33-year-old woman fell from the third floor three months before admission to our department. She received a decompressive craniectomy soon after injury. After the operation, operative incision disunion occurred due to the high pressure. Brain tissue flowed from the incision, and intracranial infection occurred. She fell into deep coma and was sent to our hospital. Her right temporal surgical incision was not healed and had a cranial defect of 10 cm × 10 cm. Her intracranial cavity was observed from the skull defect, and the brain tissue was largely lost. In addition, no brain tissue was observed by visual inspection. Cranial computed tomography showed that only a small amount of brain tissue density shadow was compressed in the cerebellum and brainstem. Four days after hospitalization in our hospital, her parents transferred her to a hospital near her hometown. The patient died six days after discharge from our hospital.
This rare case provides some proof of the importance of the brainstem in the maintenance of cardiac rhythm and vascular tension. Neurosurgeons should carefully protect brainstem neurons during operations. Clinicians can maintain the cardiac rhythm of patients who lose their major brain tissue with modern technology, but the family of the patients should be aware of death and end-life care.
Core Tip: A woman got traumatic brain injury and received decompressive craniectomy. Incision disunion and intracranial infection happened after operation, mass brain tissue flowed out from incision. The patient was in deep coma and need ventilator support, her cardiac rhythm was roughly normal. No brain tissue could be seen from cranial defect. The computed tomography showed only very few brain tissue density shadow compressed in the cerebellum and brain stem, none in rest of the cranial cavity. She died a few days later. This rare case provided us some clues that cardiac rhythm and vascular tension can be maintained with very few brain tissue.