Hao NB, Li X, Hu WW, Zhang D, Xie J, Wang XL, Li CZ. Steriod for Autoimmune pancreatitis complicating by gastric varices: A case report. World J Clin Cases 2022; 10(12): 3930-3935 [PMID: 35647173 DOI: 10.12998/wjcc.v10.i12.3930]
Corresponding Author of This Article
Chang-Zheng Li, MD, Chief Doctor, Department of Gastroenterology, PLA Rocket Force Characteristics Medical Center, No. 16 Xinjiekouwai Street, Xicheng District, Beijing 100088, China. lichangzheng435@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Apr 26, 2022; 10(12): 3930-3935 Published online Apr 26, 2022. doi: 10.12998/wjcc.v10.i12.3930
Steriod for Autoimmune pancreatitis complicating by gastric varices: A case report
Ning-Bo Hao, Xue Li, Wen-Wei Hu, Dan Zhang, Jing Xie, Xiao-Lin Wang, Chang-Zheng Li
Ning-Bo Hao, Xue Li, Wen-Wei Hu, Dan Zhang, Jing Xie, Xiao-Lin Wang, Chang-Zheng Li, Department of Gastroenterology, PLA Rocket Force Characteristics Medical Center, Beijing 100088, China
Author contributions: Hao NB and Li CZ designed the research study; Hao NB, Li X, Hu WW and Zhang D performed the research; Li X, Xie J and Wang XL contributed new reagents and analytic tools; Hao NB and Li CZ analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chang-Zheng Li, MD, Chief Doctor, Department of Gastroenterology, PLA Rocket Force Characteristics Medical Center, No. 16 Xinjiekouwai Street, Xicheng District, Beijing 100088, China. lichangzheng435@126.com
Received: September 28, 2021 Peer-review started: September 28, 2021 First decision: November 11, 2021 Revised: November 22, 2021 Accepted: March 6, 2022 Article in press: March 6, 2022 Published online: April 26, 2022
Abstract
BACKGROUND
Both autoimmune pancreatitis (AIP) and gastric varices are related to various diseases. However, AIP complicated by gastric varices is extremely rare, and has only been reported in a few studies. Here, we report a case of AIP complicated by gastric varices in a female Chinese patient.
CASE SUMMARY
A 59-year-old Chinese woman was admitted to our hospital with mild abdominal pain. Computed tomography and magnetic resonance cholangiopancreatography revealed a diffusely enlarged pancreas, an obstructed splenic vein and slight splenomegaly. Esophagogastroduodenoscopy showed gastric varices in the partial gastric fundus and the red-color sign was positive. Blood chemistry showed that IgG4 was notablely elevated. The patient was diagnosed with AIP complicated by gastric varices. Steroid therapy was administered to this patient with the risk of gastrointestinal bleeding. After one year of therapy, the pancreas, spleen and splenic vein recovered to the normal states, and the gastric varices had disappeared.
CONCLUSION
We present this case together with evidence from the literature to demonstrate the effectiveness of steroid therapy in the treatment of AIP complicated by gastric varices.
Core Tip: Autoimmune pancreatitis (AIP) complicated by gastric varices is extremely rare. We report a case of AIP complicated by gastric varices. With one year of steroid therapy, the enlarged pancreas, obstructed splenic vein and slight splenomegaly recovered to the normal states. At the same time, the gastric varices disappeared. After 3 years of follow-up, the patient did not have any of the symptoms as previously described.
