Zhang YY, Chen YL, Yi L, Gao K. IgA nephropathy treatment with traditional Chinese medicine: A case report. World J Clin Cases 2022; 10(10): 3232-3240 [PMID: 35647137 DOI: 10.12998/wjcc.v10.i10.3232]
Corresponding Author of This Article
Kun Gao, MD, Professor, Division of Nephrology, The Affiliated Hospital of Nanjing University of Chinese Medicine, No. 155 Hanzhong Road, Qinhuai District, Nanjing 210029, Jiangsu Province, China. kungao@njucm.edu.cn
Research Domain of This Article
Integrative & Complementary Medicine
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Apr 6, 2022; 10(10): 3232-3240 Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3232
IgA nephropathy treatment with traditional Chinese medicine: A case report
Ying-Yu Zhang, Yan-Lin Chen, Lan Yi, Kun Gao
Ying-Yu Zhang, Yan-Lin Chen, Lan Yi, Kun Gao, Division of Nephrology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China
Ying-Yu Zhang, Yan-Lin Chen, Lan Yi, Kun Gao, Division of Nephrology, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu Province, China
Lan Yi, Kun Gao, Inheritance Studio of Chinese Medicine Master Yan-Qin Zou, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China
Author contributions: Zhang YY wrote the paper; Chen YL and Yi L helped to collect the patient’s information; Gao K supervised Zhang YY while writing the paper and helped to revise the manuscript.
Supported byDelaying the Progression of Renal Failure in Chronic Kidney Disease Project, No. JD2019SZ10 and Jiangsu Chinese Medicine Science and Technology Development Projects, No. YB201913.
Informed consent statement: Informed written consent was obtained from the patient’ parents for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kun Gao, MD, Professor, Division of Nephrology, The Affiliated Hospital of Nanjing University of Chinese Medicine, No. 155 Hanzhong Road, Qinhuai District, Nanjing 210029, Jiangsu Province, China. kungao@njucm.edu.cn
Received: November 21, 2021 Peer-review started: November 21, 2021 First decision: December 27, 2021 Revised: January 9, 2022 Accepted: February 23, 2022 Article in press: February 23, 2022 Published online: April 6, 2022 Processing time: 127 Days and 20.2 Hours
Abstract
BACKGROUND
IgA nephropathy (IgAN) is a common primary glomerular disease that leads to end-stage renal disease with poor therapy efficacy. Traditional Chinese medicine (TCM) is effective in the treatment of IgAN and has the potential to become an alternative treatment for IgAN. Professor Yan-Qin Zou is a nephropathy expert, a National Chinese Medicine Master, and an heir to the Menghe School of Medicine.
CASE SUMMARY
A 28-year-old man had positive urinary protein and elevated serum creatinine (Scr) results and was diagnosed with IgAN 2-3 years prior to the outpatient department visit at our hospital in 2017. Professor Zou used the following methods to treat the patient: Invigorating the spleen and tonifying the kidney, removing dampness and clearing turbidity, quickening the blood and transforming stasis, and freeing vessels and regulating collaterals. She adjusted the prescription in accordance with the patient’s symptoms. After 6 mo of treatment, the symptoms had resolved and serological indexes were also decreased [Scr from 288.5 to 188.6 µmol/L, blood urea nitrogen (BUN) from 10.9 to 9.5 mmol/L, serum uric acid (UA) from 612 to 503 µmol/L]. During follow-up, BUN, Scr, and UA levels remained stable.
CONCLUSION
Professor Zou’s therapeutic strategy to treat IgAN using TCM was efficacious and a good reference for application.
Core Tip: IgA nephropathy (IgAN) is a common primary glomerular disease leading to end-stage renal disease with poor prognosis. Traditional Chinese medicine (TCM) is an alternative treatment for IgAN. Professor Yan-Qin Zou, one of the National Chinese Medicine Masters, has accumulated rich and unique experience in TCM diagnosis and treatment of nephropathy. This case report analyses an IgAN patient receiving TCM treatment with satisfying clinical efficacy. Professor Zou’s therapeutic strategy to treat IgAN using TCM was efficacious and a good reference for clinical application.
