Case Report
Copyright ©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Clin Cases. Jul 16, 2013; 1(4): 146-148
Published online Jul 16, 2013. doi: 10.12998/wjcc.v1.i4.146
Noncoronary sinus of Valsalva rupture into the right atrium with a coexisting perimembranous ventricular septal defect
Long-Bao Cao, David Hannon, Assad Movahed
Long-Bao Cao, David Hannon, Assad Movahed, Department of Cardiovascular Sciences, East Carolina University, Brody School of Medicine, East Carolina Heart Institute, Greenville, NC 27858, United States
Author contributions: Cao LB, Hannon D and Movahed A contributed to the manuscript writing and revision.
Supported by The “East Carolina Heart Institute”
Correspondence to: Assad Movahed, MD, Department of Cardiovascular Sciences, East Carolina University, Brody School of Medicine, East Carolina Heart Institute, 115 Heart Drive, Mail Stop 651, Greenville, NC 27858, United States. movaheda@ecu.edu
Telephone: +1-832-3731447 Fax: +1-252-7447724
Received: January 30, 2013
Revised: May 14, 2013
Accepted: June 1, 2013
Published online: July 16, 2013
Abstract

Ruptured sinus of Valsalva is very uncommon, and is < 1% of all congenital defects. The incidence ranges from 0.1%-3.5%. There is a male to female predominance of 4:1, with the highest incidence in the Asian population. Higher incidence is also seen in patients with Marfan’s syndrome and Ehlers Danlos syndrome. There is a higher association of ruptured sinus of Valsalva with ventricular septal defect (VSD), aortic stenosis, and bicuspid valve defect. While most patients with VSD often have rupture of their right coronary sinus of Valsalva into the right ventricle due to poor structural integrity, we present a rare case of a patient with VSD who had rupture of his noncoronary sinus of Valsalva into the right atrium.

Keywords: Sinus of Valsalva, Rupture, Ventricular septal defect, Wind sock deformity

Core tip: It is important to understand that aneurysms and or rupture of the coronary sinus of Valsalva can occur from any sinus and into any chamber, which will affect management and treatment.