Published online Jul 16, 2013. doi: 10.12998/wjcc.v1.i4.140
Revised: May 30, 2013
Accepted: June 8, 2013
Published online: July 16, 2013
Diarrhea and cholera are major health problems. Vibrio cholera, the causative agent of cholera, infects the small intestine, resulting in vomiting, massive watery diarrhea and dehydration. Reduced water and electrolyte absorption is also due to zinc deficiency. Zinc has an important role in recovery from the disease. The combination of zinc with cholera vaccine and oral rehydration solutions has a positive impact on cholera and diarrhea. It has led to a decrease in the mortality and morbidity associated with diarrhea.
Core tip: In diarrhea and cholera, reduced water and electrolyte absorption is due to zinc deficiency. Therefore, zinc has an important role in recovery from the symptoms. The use of zinc with cholera vaccine and oral rehydration solutions has been shown to affect positive impacts in cholera and diarrhea.