Case Report
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World J Clin Cases. Jun 16, 2013; 1(3): 128-133
Published online Jun 16, 2013. doi: 10.12998/wjcc.v1.i3.128
Peripheral cemento-ossifying fibroma: A case report with review of literature
Amit Kumar Mishra, Rahul Maru, Shrikant Vishnuprasad Dhodapkar, Gagan Jaiswal, Rajesh Kumar, Heena Punjabi
Amit Kumar Mishra, Rahul Maru, Shrikant Vishnuprasad Dhodapkar, Gagan Jaiswal, Rajesh Kumar, Heena Punjabi, Sri Aurobindo Institute of Dentistry and Post Graduate Institute, Indore 452018, India
Author contributions: Mishra AK contributed substantially to conception and design, acquisition of data, analysis and interpretation of data: diagnosis, motivation, surgical treatment follow up and data collection, final approval of the version to be published; Maru R and Dhodapkar SV contributed to first draft of the article and revision as suggested by reviewers; Jaiswal G contributed to the drafting, corrections, second revision for important intellectual content, and contributed to histopathological analysis; Kumar R and Punjabi H contributed to the drafting the article, revising it critically for important intellectual content, corrections, second revision.
Correspondence to: Amit Kumar Mishra, MD, Assistant Professor, Sri Aurobindo Institute of Dentistry and Post Graduate Institute, Indore Ujjain State Highway, Near MR 10 Crossing, Sanwer Road, Indore 452018, India. dramitluvsu@gmail.com
Telephone: +91-922-9585073 Fax: +91-731-4231010
Received: February 28, 2013
Revised: April 19, 2013
Accepted: May 8, 2013
Published online: June 16, 2013
Processing time: 106 Days and 0.1 Hours
Abstract

Peripheral cemento-ossifying fibroma (PCOF) is a rare osteogenic neoplasm that ordinarily presents as an epulis-like growth. This is of a reactive rather than neoplastic nature and its pathogenesis is uncertain. PCOF predominantly affects adolescent and young adults with greatest prevalence around 28 years. We report here a rare clinical case of PCOF of the mandible, 1 cm mesiodistally and 1.5 cm occluso-gingivally in diameter, which caused difficulty in eating and speech, in a 42-year-old female patient. She was asymptomatic for 1 year and on follow-up for 6 mo post surgically showed gingival health and normal radioopacity of bone without any recurrence. Clinical, radiographic and histological characteristics are discussed and recommendations regarding differential diagnosis, treatment and follow up are provided. The controversial varied nomenclature and possible etiopathogenesis of PCOF are emphasized.

Keywords: Peripheral cemento-ossifying fibroma; Gingivectomy; Granuloma

Core tip: The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium. The pathogenesis of this tumor is uncertain. Due to their clinical and histopathological similarities, some peripheral cemento ossifying fibromas (PCOFs) are believed to show fibrous maturation and subsequent calcification. The diagnosis of PCOF based only on clinical observation is difficult, hence radiographs and histopathological examination are essential for accurate diagnosis. In addition, a complete excision of the lesion is required to prevent reoccurrence.