Case Report
Copyright ©2013 Baishideng. All rights reserved.
World J Clin Cases. Apr 16, 2013; 1(1): 49-51
Published online Apr 16, 2013. doi: 10.12998/wjcc.v1.i1.49
Schwannoma of the rectum: A case report and literature review
Maddalena Zippi, Roberta Pica, Renzo Scialpi, Claudio Cassieri, Eleonora Veronica Avallone, Giuseppe Occhigrossi
Maddalena Zippi, Roberta Pica, Claudio Cassieri, Eleonora Veronica Avallone, Giuseppe Occhigrossi, Department of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, 00157 Rome, Italy
Renzo Scialpi, Department of Pathology, Sandro Pertini Hospital, 00157 Rome, Italy
Author contributions: Pica R made substantial contribution to study conception and design; Cassieri C and Scialpi R were involved in acquisition, analysis and interpretation of data; Zippi M and Avallone EV were involved in drafting the article and revising it critically for important intellectual content; Occhigrossi G gave final approval of the version to be published.
Correspondence to: Maddalena Zippi, MD, Department of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, Via dei Monti Tiburtini 385, 00157 Rome, Italy. maddyzip@yahoo.it
Telephone: +39-6-41735005 Fax: +39-6-41735005
Received: December 29, 2012
Revised: January 29, 2013
Accepted: February 8, 2013
Published online: April 16, 2013
Processing time: 101 Days and 22.8 Hours
Abstract

Schwannoma is a tumor originating from the Schwann cells. Gastrointestinal schwannomas are uncommon stromal tumors of the intestinal tract and, in particular, rectal schwannomas are extremely rare. In fact, it is well established that schwannomas appear more frequently in the stomach and in the small intestine, while location in the colon or in the rectum is uncommon. Reading the literature, only few cases of rectal schwannoma have been reported. Their diagnosis is confirmed by the immunohistochemical panel (S-100 protein). When these tumors are located in the colon and in the rectum, radical excision with wide margins is mandatory, due to their tendency to recur locally or become malignant, if left untreated. In the present study, we describe a case of a rectal schwannoma occured in a 72-year-old man, presented as a small polypoid lesion, which was successfully removed in toto by hot-biopsy, during the same endoscopy, due to the dimensons. No recurrence of the lesion was observed after 6 mo of follow-up.

Keywords: Rectum; Schwannoma; Immunohistochemistry; S-100 protein; Treatment

Core tip: Schwannomas of the colon and rectum are tumors that are rarely detected. For achieving a definitive histopathological diagnosis, the use of an appropriate immunohistochemical panel is request. Although schwannomas are considered to be benign tumors, their risks of recurrence must be not ignored. The best therapeutic option is complete surgical removal. In the present study, we describe a case of a rectal schwannoma occured in a 72-year-old man, presented as a small sessile polypoid lesion, which was successfully removed in toto by hot-biopsy, during the same procedure. No recurrence of the lesion was observed after 6 mo of follow-up.