Review
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Mar 20, 2024; 14(1): 89196
Published online Mar 20, 2024. doi: 10.5662/wjm.v14.i1.89196
Update on the gut microbiome in health and diseases
Maurizio Salvadori, Giuseppina Rosso
Maurizio Salvadori, Department of Renal Transplantation, Careggi University Hospital, Florence 50139, Tuscany, Italy
Giuseppina Rosso, Division of Nephrology, San Giovanni di Dio Hospital, Florence 50143, Toscana, Italy
Author contributions: Salvadori M and Rosso G equally contributed to the development of the manuscript; Salvadori M and Rosso G wrote the manuscript; Rosso G looked for new references; Both authors reviewed the final manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maurizio Salvadori, MD, Professor, Department of Renal Transplantation, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Tuscany, Italy. maurizio.salvadori1@gmail.com
Received: October 23, 2023
Peer-review started: October 23, 2023
First decision: December 6, 2023
Revised: December 18, 2023
Accepted: January 27, 2024
Article in press: January 27, 2024
Published online: March 20, 2024
Processing time: 135 Days and 20.2 Hours
Core Tip

Core Tip: Gut microbiome has relevant importance in healthy and diseased subjects. The production of several metabolites from the gut microbiome influences the immune system, brain, lung, heart, and metabolism. In the case of normal indigenous microbiota, metabolites produced have a benign action and contribute to the health. By contrast, the presence of pathobionts with their products may affect the different organs and produce diseases. The study of the gut microbiome is a difficult one and different omics technologies should be applied. The large quantity of studies highlights the relevance of the gut microbiome in health and disease.