Wang GB, Zhang XF, Liang B, Lei J, Xue J. Improving treatment plan and mental health in children with abdominal infection for broad-spectrum bacterial infections. World J Psychiatry 2024; 14(9): 1319-1325 [DOI: 10.5498/wjp.v14.i9.1319]
Corresponding Author of This Article
Gui-Bo Wang, MM, Attending Doctor, Department of Pediatric Surgery, the First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Qiaoxi District, Zhangjiakou 075000, Hebei Province, China. heibaizhubobo@163.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Sep 19, 2024; 14(9): 1319-1325 Published online Sep 19, 2024. doi: 10.5498/wjp.v14.i9.1319
Improving treatment plan and mental health in children with abdominal infection for broad-spectrum bacterial infections
Gui-Bo Wang, Xue-Feng Zhang, Bing Liang, Jie Lei, Jun Xue
Gui-Bo Wang, Xue-Feng Zhang, Bing Liang, Jie Lei, Department of Pediatric Surgery, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China
Jun Xue, Department of General Surgery, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China
Author contributions: Wang GB, Lei J, Xue J were the guarantors and designed the study; Wang GB, Liang B, Zhang XF participated in the acquisition, analysis, and interpretation of the data, and drafted the initial manuscript; Wang GB revised the article critically for important intellectual content.
Supported byZhangjiakou Science and Technology Tackling Program, No. 2021099D.
Institutional review board statement: The study was reviewed and approved by the Science and Research Office of the First Affiliated Hospital of Hebei North University.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gui-Bo Wang, MM, Attending Doctor, Department of Pediatric Surgery, the First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Qiaoxi District, Zhangjiakou 075000, Hebei Province, China. heibaizhubobo@163.com
Received: July 24, 2024 Revised: August 14, 2024 Accepted: August 15, 2024 Published online: September 19, 2024 Processing time: 48 Days and 19.1 Hours
Core Tip
Core Tip: Preliminary nucleic acid detection of broad-spectrum bacterial infections has important clinical significance in the surgical treatment of abdominal infections in children. The results of this study show that compared with only intraoperative bacterial culture + drug sensitivity testing, early broad-spectrum bacterial infection nucleic acid testing can significantly improve patients' treatment effects, mental health and recovery quality, and reduce medical costs. First of all, conducting broad-spectrum bacterial infection nucleic acid detection in advance can help identify pathogens earlier and guide the rational use of antibiotics, thereby effectively controlling the development of infection. The postoperative infection indicators of the patients in the observation group were significantly lower than those of the control group, and the hospitalization time and costs were also significantly reduced, which further verified the clinical value of nucleic acid testing in advance. This research result has guiding significance for clinical practice and also provides an important reference for future related research.
