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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Dec 19, 2024; 14(12): 1836-1844
Published online Dec 19, 2024. doi: 10.5498/wjp.v14.i12.1836
Published online Dec 19, 2024. doi: 10.5498/wjp.v14.i12.1836
Depression and anxiety, peripheral blood inflammatory factors, and stress levels on therapeutic outcomes in patients with chronic wounds
Bo Li, Xiang-Rong Xu, Department of Burns and Plastic Surgery, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415000, Hunan Province, China
Cha Li, Department of Pediatric Intensive Care Unit, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415000, Hunan Province, China
Xian-Jiang Zhong, Department of Psychiatry, The First People’s Hospital of Xiantao, Xiantao 433099, Hubei Province, China
Author contributions: Li B and Xu XR designed the study; Li B and Li C performed data extraction and wrote the manuscript; Zhong XJ provided professional support; and all authors read and approved the final version.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), approval No. 2024-148-01.
Informed consent statement: The informed consent was waived by the Institutional Review Board.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The anonymous data used in this study can be obtained from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiang-Rong Xu, Chief Physician, Department of Burns and Plastic Surgery, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), No. 818 Renmin Road, Wuling District, Changde 415000, Hunan Province, China. 13973661455@163.com
Received: September 25, 2024
Revised: October 29, 2024
Accepted: November 8, 2024
Published online: December 19, 2024
Processing time: 63 Days and 3.5 Hours
Revised: October 29, 2024
Accepted: November 8, 2024
Published online: December 19, 2024
Processing time: 63 Days and 3.5 Hours
Core Tip
Core Tip: This study retrospectively analyzed clinical data from 110 patients with chronic wounds to assess the effects of depressive and anxious moods, peripheral blood inflammatory markers, and stress levels on treatment outcomes. The results showed an overall efficacy rate of 86.36%, with independent risk factors identified as wound size and depression/anxiety levels. Additionally, peripheral blood inflammatory markers and stress levels were lower in the effective group than in the ineffective group. Therefore, for patients with chronic wound, it is crucial to address not only the wounds but also their psychological well-being and inflammatory stress status to improve treatment effectiveness.