Martins AL, Fróes RSB, Zago-Gomes MP. Prevalence, phenotype and medication for the pediatric inflammatory bowel disease population of a state in Southeastern Brazil. World J Clin Pediatr 2022; 11(4): 341-350 [PMID: 36052115 DOI: 10.5409/wjcp.v11.i4.341]
Corresponding Author of This Article
Adalberta Lima Martins, MSc, Doctor, Pharmaceutical Assistance, Health Department of Espírito Santo, Desembargador Ferreira Coelho 330/315 Praia do Suá, Ed. Eldorado, Vitoria 29052-210, Espírito Santo, Brazil. limambeta@uol.com.br
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Pediatr. Jul 9, 2022; 11(4): 341-350 Published online Jul 9, 2022. doi: 10.5409/wjcp.v11.i4.341
Prevalence, phenotype and medication for the pediatric inflammatory bowel disease population of a state in Southeastern Brazil
Adalberta Lima Martins, Renata de Sá Brito Fróes, Maria da Penha Zago-Gomes
Adalberta Lima Martins, Pharmaceutical Assistance, Health Department of Espírito Santo, Vitoria 29052-210, Espírito Santo, Brazil
Renata de Sá Brito Fróes, Department of Gastroenterology, Gastromed, Rio de Janeiro 22640-100, Rio de Janeiro, Brazil
Maria da Penha Zago-Gomes, Departament of Medical Clinical, Hospital Universitário Cassiano Antonio Moraes, Vitoria 29042-755, Espírito Santo, Brazil
Author contributions: Martins AL contributed to concept, design of the research, collection of the data, analysis, interpretation, and writing; Fróes RSB contributed to interpretation, writing and review; Zago-Gomes MP contributed to analyses study, statistical analysis, interpretation, and writing.
Institutional review board statement: This study was approved by the Ethics and Research Committee of the Nossa Senhora da Gloria Children’s Hospital (CAAE 19602813.8.0000.5069) after obtaining authorization from the State Office for Pharmaceutical Assistance. The term of clarification and consent was waived because the data used is secondary data.
Informed consent statement: The terms of clarification and responsibility were not necessary because the information used were secondary data from Espírito Santo's State Health Department documents.
Conflict-of-interest statement: All the authors have no conflicts of interest to disclose related to the manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Adalberta Lima Martins, MSc, Doctor, Pharmaceutical Assistance, Health Department of Espírito Santo, Desembargador Ferreira Coelho 330/315 Praia do Suá, Ed. Eldorado, Vitoria 29052-210, Espírito Santo, Brazil. limambeta@uol.com.br
Received: January 7, 2022 Peer-review started: January 7, 2022 First decision: March 9, 2022 Revised: March 23, 2022 Accepted: June 3, 2022 Article in press: June 3, 2022 Published online: July 9, 2022 Processing time: 179 Days and 20.4 Hours
ARTICLE HIGHLIGHTS
Research background
Pediatric inflammatory bowel disease in a region of Brazil.
Research motivation
The pediatric inflammatory bowel disease data are practically unknown in Brazil and South America.
Research objectives
To determine the epidemiology of pediatric inflammatory bowel disease and its characteristics in Brazil and South America.
Research methods
The data were retrieved from the Public Medication-Dispensing System of the Department of Health in Espírito Santo state of Brazil.
Research results
The prevalence and incidence in pediatric ages are higher than those in other regions in Latin America. More severe disease was observed in the youngest patients. Pancolitis is more frequent in ulcerative colitis, and fistulizing and perianal disease are more frequent in Crohn's disease. Use of biological therapy was compared in the pediatric and adult groups.
Research conclusions
We have little data on inflammatory bowel disease in Latin America. We need to better understand the epidemiology, phenotype and medication used for the treatment of inflammatory bowel disease in each region.
Research perspectives
Obtain better therapeutic approaches and contribute to the planning of public health actions.
