Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jul 18, 2015; 6(6): 462-468
Published online Jul 18, 2015. doi: 10.5312/wjo.v6.i6.462
Published online Jul 18, 2015. doi: 10.5312/wjo.v6.i6.462
Use of bone marrow derived stem cells in trauma and orthopaedics: A review of current concepts
Philip S Pastides, Wasim S Khan, University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, Middlesex HA7 4LP, United Kingdom
Matthew J Welck, Wexham Park Hospital, Slough, West Berkshire SL2 4HL, United Kingdom
Author contributions: Pastides PS, Welck MJ and Khan WS all collected, wrote, edited and approved the final version of the manuscript.
Conflict-of-interest statement: The authors declare no conflicting interests attached to this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Wasim S Khan, MBChB, MSc, PhD, FRCS (Tr and Orth), Orthopaedic Registrar, Clinical Lecturer, University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex HA7 4LP, United Kingdom. wasimkhan@doctors.org.uk
Telephone: +44-20-889542300 Fax: +44-20-7679200
Received: February 8, 2015
Peer-review started: February 9, 2015
First decision: April 10, 2015
Revised: May 7, 2015
Accepted: May 27, 2015
Article in press: May 28, 2015
Published online: July 18, 2015
Processing time: 155 Days and 20.9 Hours
Peer-review started: February 9, 2015
First decision: April 10, 2015
Revised: May 7, 2015
Accepted: May 27, 2015
Article in press: May 28, 2015
Published online: July 18, 2015
Processing time: 155 Days and 20.9 Hours
Core Tip
Core tip: Tissue engineering techniques using bone marrow-derived stem cells is an attractive, promising and growing area of research within the field of trauma and orthopaedics. There are plenty of in vitro and animal studies showing the benefits of such treatments with a slow and steady growth of human in vivo studies emerging.