Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Aug 24, 2024; 15(8): 1110-1116
Published online Aug 24, 2024. doi: 10.5306/wjco.v15.i8.1110
Non-Hodgkin's lymphoma involving chronic difficult-to-heal wounds: A case report
Pei-Shen Zhang, Rong Wang, Hu-Wen Wu, Han Zhou, Han-Bin Deng, Wen-Xuan Fan, Jia-Cheng Li, Shao-Wen Cheng
Pei-Shen Zhang, Rong Wang, Hu-Wen Wu, Han Zhou, Han-Bin Deng, Wen-Xuan Fan, Jia-Cheng Li, Shao-Wen Cheng, Department of Wound Repair, Key Laboratory of Emergency and Trauma of Ministry of Education, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, Hainan Province, China
Co-first authors: Pei-Shen Zhang and Rong Wang.
Author contributions: Zhang PS and Wang Y contributed to manuscript writing and editing, and data collection; Wu HW, Zhou H, Deng HB, Fan WX, and Li JC contributed to data analysis; Cheng SW contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Supported by Natural Science Foundation of Hainan Province, China, No. 822MS174.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shao-Wen Cheng, PhD, Associate Chief Physician, Department of Wound Repair, Key Laboratory of Emergency and Trauma of Ministry of Education, The First Affiliated Hospital of Hainan Medical University, No. 31 Longhua Road, Haikou 570102, Hainan Province, China. chengshaowen1@126.com
Received: May 15, 2024
Revised: July 10, 2024
Accepted: July 16, 2024
Published online: August 24, 2024
Processing time: 92 Days and 15 Hours
Core Tip

Core Tip: Non-Hodgkin's lymphoma represents the majority of lymphoma cases, and extranodal natural killer/T-cell lymphoma, a rare subtype, is characterized by its rarity, high aggressiveness, and poor prognosis. Skin lesions typically present as nodules and hard lumps, with wounds in the lower limbs being relatively uncommon. Here we present the case of a 19-year-old male diagnosed with non-Hodgkin's lymphoma due to an 11-month history of chronic skin breakdown with effusion on the left lower leg near the ankle. Conventional radiotherapy and wound care resulted in poor wound healing. However, after undergoing radiotherapy followed by wound enlargement excision debridement combined with peroneal artery perforator flap grafting, the wound healed successfully.