Published online Dec 28, 2022. doi: 10.4329/wjr.v14.i12.375
Peer-review started: September 9, 2022
First decision: October 12, 2022
Revised: October 24, 2022
Accepted: December 1, 2022
Article in press: December 1, 2022
Published online: December 28, 2022
Processing time: 103 Days and 23.2 Hours
Bleeding in the gastrointestinal tract is common and transarterial embolization enables the clinician to control gastrointestinal bleeding. Contrast extravasation is a prerequisite for successful embolization. Provocative angiography is helpful in the detection of elusive bleeding.
We performed a retrospective analysis of angiographic treatment in patients with lower gastrointestinal hemorrhage and initially negative angiographies, as well as the role of norepinephrine (NE) in unmasking bleeding.
We analyzed 41 patients with lower gastrointestinal bleeding after angiography who had undergone treatment over a period of 10 years. All patients had a positive shock index and needed intensive care.
In three of four patients, angiography disclosed the site of bleeding when NE was used during the procedure for hemodynamic stabilization.
We suggest that angiography performed after the administration of NE in unstable patients with gastrointestinal bleeding and an initially negative angiography has the potential to unmask bleeding sites for successful embolization. However, this statement must be confirmed in prospective studies.
Core Tip: Bleeding in the gastrointestinal tract is common in hospital emergency settings. Gastrointestinal endoscopy is currently the undisputed method of choice for achieving hemostasis. Provocative angiography has been reported to help in the detection of elusive bleeding. We performed a retrospective analysis of angiographic management of bleeding in the lower gastrointestinal tract (LGIB). In a small number of patients, hemodynamic stabilization with norepinephrine (NE) disclosed LGIB which had escaped detection until this time. Angiography after administration of NE unmasked bleeding in three of four patients. We saw no complications in two of three patients after embolization. It may be assumed that this method can detect bleeding successfully and help to achieve hemostasis by angiography.