Meta-Analysis
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Nov 26, 2020; 12(11): 550-558
Published online Nov 26, 2020. doi: 10.4330/wjc.v12.i11.550
Effects of left ventricular assist device on pulmonary functions and pulmonary hemodynamics: A meta-analysis
Waqas Ullah, Casey Meizinger, Zain Ali, Ankur Panchal, Rehan Saeed, Donald C Haas, Eduardo Rame
Waqas Ullah, Casey Meizinger, Zain Ali, Rehan Saeed, Department of Internal Medicine, Abington Jefferson Health, Abington, PA 19001, United States
Ankur Panchal, Department of Internal Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States
Donald C Haas, Department of Cardiology, Abington Jefferson Health, Abington, PA 19001, United States
Eduardo Rame, Department of Cardiology, Thomas Jefferson University, Abington, PA 19001, United States
Author contributions: Ullah W contributed to conceptualization, analysis, and manuscript writing; Meizinger C contributed to manuscript writing and data collection; Ali Z contributrd to revision; Panchal A contributed to data curation; Saeed R contributed to editing; Haas DC and Rame E contributed to supervision.
Conflict-of-interest statement: The authors have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Waqas Ullah, MD, Doctor, Department of Internal Medicine, Abington Jefferson Health, 1200 Old York Road, Abington, PA 19001, United States. waqasullah.dr@gmail.com
Received: April 28, 2020
Peer-review started: April 28, 2020
First decision: July 5, 2020
Revised: July 18, 2020
Accepted: October 30, 2020
Article in press: October 30, 2020
Published online: November 26, 2020
Processing time: 211 Days and 16.5 Hours
Core Tip

Core Tip: Left ventricular assist device (LVAD) implantation can cause worsening of forced expiratory volume in one second, forced vital capacity, and diffusion lung capacity of carbon monoxide in post-LVAD patients. However, the benefits of LVAD implantation outweigh its risks in the context of pulmonary hemodynamics. More large scale studies are required to validate our findings.