Samanidis G, Kanakis M, Georgiou C, Perreas K. Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection. World J Cardiol 2022; 14(4): 231-238 [PMID: 35582464 DOI: 10.4330/wjc.v14.i4.231]
Corresponding Author of This Article
George Samanidis, MD, PhD, Consultant Cardiac Surgeon, Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, 356 Syggrou Avenue, Athens 17674, Greece. gsamanidis@yahoo.gr
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Apr 26, 2022; 14(4): 231-238 Published online Apr 26, 2022. doi: 10.4330/wjc.v14.i4.231
Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
George Samanidis, Meletios Kanakis, Charalampos Georgiou, Konstantinos Perreas
George Samanidis, Charalampos Georgiou, Konstantinos Perreas, Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, Athens 17674, Greece
Meletios Kanakis, Department of Pediatric and Congenital Heart Surgery, Onassis Cardiac Surgery Center, Athens 17674, Greece
Author contributions: All authors contributed equally in carrying out the research and writing the manuscript.
Institutional review board statement: The study was approved by our hospital’s institutional review board (No. 546/30-04-2015).
Conflict-of-interest statement: All authors declare that there are no any conflicts of interest to disclose.
Data sharing statement: Data are available upon request from the authors.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: George Samanidis, MD, PhD, Consultant Cardiac Surgeon, Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, 356 Syggrou Avenue, Athens 17674, Greece. gsamanidis@yahoo.gr
Received: December 5, 2021 Peer-review started: December 5, 2021 First decision: January 25, 2022 Revised: February 2, 2022 Accepted: April 3, 2022 Article in press: April 3, 2022 Published online: April 26, 2022 Processing time: 134 Days and 5.8 Hours
ARTICLE HIGHLIGHTS
Research background
Acute type A aortic dissection (ATAAD) is a life-threatening cardiovascular disease. Current guidelines recommend that ascending aortic replacement be performed when the ascending aorta is 5.5 cm in non-syndromic patients, while in syndormic patients, it should be replaced if the diameter reaches 4.5 cm in the sinus of Valsalva and 5.0 cm in the ascending aorta.
Research motivation
New approach for ascending aorta aneurysm management should be considered for prevention of ATAAD.
Research objectives
The objective of our study was to evaluate the correlation of the diameter of dissected ascending aorta in patients with ATAAD with preoperative adverse events, such as neurological dysfunctions and hemodynamic instability.
Research methods
A retrospective analysis was performed on patients who were admitted to our hospital for ATAAD treatment. In all patients, the diameter of dissected ascending aorta was measured and its association with adverse events was analyzed.
Research results
The diameter of dissected ascending aorta was not associated with adverse events. Also, the diameter of the ascending aorta was not associated with 30-d mortality and ICU and hospital stay postoperatively.
Research conclusions
Maybe the threshold of ascending aorta aneurysm should be revised for lower limits regarding the risk for late acute dissection
Research perspectives
Randomized controlled studies including more patients should be performed to confirm our results and preventive ascending aorta replacement may be considered for prevention of ATAAD.
