Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Apr 26, 2022; 14(4): 231-238
Published online Apr 26, 2022. doi: 10.4330/wjc.v14.i4.231
Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
George Samanidis, Meletios Kanakis, Charalampos Georgiou, Konstantinos Perreas
George Samanidis, Charalampos Georgiou, Konstantinos Perreas, Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, Athens 17674, Greece
Meletios Kanakis, Department of Pediatric and Congenital Heart Surgery, Onassis Cardiac Surgery Center, Athens 17674, Greece
Author contributions: All authors contributed equally in carrying out the research and writing the manuscript.
Institutional review board statement: The study was approved by our hospital’s institutional review board (No. 546/30-04-2015).
Conflict-of-interest statement: All authors declare that there are no any conflicts of interest to disclose.
Data sharing statement: Data are available upon request from the authors.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: George Samanidis, MD, PhD, Consultant Cardiac Surgeon, Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, 356 Syggrou Avenue, Athens 17674, Greece. gsamanidis@yahoo.gr
Received: December 5, 2021
Peer-review started: December 5, 2021
First decision: January 25, 2022
Revised: February 2, 2022
Accepted: April 3, 2022
Article in press: April 3, 2022
Published online: April 26, 2022
Processing time: 134 Days and 5.8 Hours
Abstract
BACKGROUND

Acute type A aortic dissection (ATAAD) is a life-threatening disease associated with high morbidity and mortality.

AIM

To evaluate the diameter of dissected ascending aorta in patients diagnosed with ATAAD and whether the aortic diameter is associated with preoperative adverse events.

METHODS

A total of 108 patients diagnosed with ATAAD who underwent emergency operation under hypothermic circulatory arrest were enrolled in this study. Demographic characteristics and perioperative data were recorded. In all patients, preoperative chest and abdomen computed tomography (CT) scans were performed.

RESULTS

Median age of the patients was 61.5 (52.5-70.5) years and median body mass index (BMI) was 28.2 (25.1-32.6) cm2. The number of female patients was 37 (25%). Median diameter of the ascending aorta was 5.0 (4.5-6) cm and 53.8% of the patients had an aortic diameter < 5.0 cm, while 32.3% of the patients had an aortic diameter of 4.5cm and 72.0% had an ascending aorta diameter < 5.5 cm. The diameter of the ascending aorta did not differ in patients with vs without preoperative adverse events: Preoperative neurological dysfunction (P = 0.53) and hemodynamic instability (P = 0.43). Median age of patients with preoperative hemodynamic instability was 65 (57.5-74) years, while it was 60 (51-68) years in patients without (P = 0.04)

CONCLUSION

Although current guidelines suggest replacing the ascending aorta with a diameter > 5.5 cm, most of the patients with ATAAD had an aortic diameter of less than 5.5 cm. The diameter of the ascending aorta in patients diagnose with ATAAD is not associated with preoperative adverse events.

Keywords: Acute, Aortic dissection, Type A, Ascending aorta, Diameter

Core Tip: Do patients with an ascending aorta diameter < 5.5 cm undergo more aggressive surgery for prevention of acute type A aortic dissection (ATAAD)? Most of the patients (72.0%) with ATAAD had an ascending aorta diameter < 5.5 cm. An international taskforce should adapt the new data extracted from the most recent scientific evidence in the surgical treatment of the ascending aortic aneurysm.