Liang JJ, Dixit S, Santangeli P. Mechanisms and clinical significance of early recurrences of atrial arrhythmias after catheter ablation for atrial fibrillation. World J Cardiol 2016; 8(11): 638-646 [PMID: 27957250 DOI: 10.4330/wjc.v8.i11.638]
Corresponding Author of This Article
Jackson J Liang, DO, Division of Cardiology, Electrophysiology Section, Hospital of the University of Pennsylvania, 3400 Spruce Street, 8 Gates Building, Philadelphia, PA 19104, United States. jackson.liang@uphs.upenn.edu
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Nov 26, 2016; 8(11): 638-646 Published online Nov 26, 2016. doi: 10.4330/wjc.v8.i11.638
Mechanisms and clinical significance of early recurrences of atrial arrhythmias after catheter ablation for atrial fibrillation
Jackson J Liang, Sanjay Dixit, Pasquale Santangeli
Jackson J Liang, Sanjay Dixit, Pasquale Santangeli, Division of Cardiology, Electrophysiology Section, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States
Author contributions: Liang JJ, Dixit S and Santangeli P contributed to this paper.
Conflict-of-interest statement: The authors report no relevant conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jackson J Liang, DO, Division of Cardiology, Electrophysiology Section, Hospital of the University of Pennsylvania, 3400 Spruce Street, 8 Gates Building, Philadelphia, PA 19104, United States. jackson.liang@uphs.upenn.edu
Telephone: +1-215-6624000 Fax: +1-215-6150829
Received: August 13, 2016 Peer-review started: August 15, 2016 First decision: September 2, 2016 Revised: September 6, 2016 Accepted: September 13, 2016 Article in press: September 18, 2016 Published online: November 26, 2016 Processing time: 103 Days and 7.5 Hours
Abstract
Early recurrence of atrial arrhythmias (ERAA) after ablation is common and strongly predicts late recurrences and ablation failure. However, since arrhythmia may eventually resolve in up to half of patients with ERAA, guidelines do not recommend immediate reintervention for ERAA episodes occurring during a 3-mo post-ablation blanking period. Certain clinical demographic, electrophysiologic, procedural, and ERAA-related characteristics may predict a higher likelihood of long-term ablation failure. In this review, we aim to discuss potential mechanisms of ERAA, and to summarize the clinical significance, prognostic implications, and treatment options for ERAA.
Core tip: There have been several studies examining the predictors of early recurrences of atrial arrhythmias (ERAA) during the blanking period after atrial fibrillation (AF) ablation and the predictive value of such early recurrences on late recurrences. In this review, we summarize the mechanisms and predictors, clinical significance, prognostic implications, and treatment options of ERAA after AF ablation.
