Published online Feb 26, 2022. doi: 10.4330/wjc.v14.i2.64
Peer-review started: March 20, 2021
First decision: June 17, 2021
Revised: July 4, 2021
Accepted: January 29, 2022
Article in press: January 29, 2022
Published online: February 26, 2022
Processing time: 333 Days and 3.2 Hours
Exercise stress echocardiography (ESE) is a widely used diagnostic test in cardiology departments. ESE is mainly used to study patients with coronary artery disease; however, it has increasingly been used in other clinical scenarios including valve pathology, congenital heart disease, hypertrophic and dilated cardiomyopathies, athlete evaluations, diastolic function evaluation, and pulmonary circulation study. In our laboratories, we use an established methodology in which cardiac function is evaluated while exercising on a treadmill. After completing the exercise regimen, patients remain in a standing position or lie down on the left lateral decubitus, depending on the clinical questions to be answered for further evaluation. This method increases the quality and quantity of information obtained. Here, we present the various methods of exercise stress echocardiography and our experience in many clinical arenas in detail. We also present alternatives to ESE that may be used and their advantages and disadvantages. We review recent advances in ESE and future directions for this established method in the study of cardiac patients and underline the advantage of using a diagnostic tool that is radiation-free.
Core Tip: The fair cost, safety, diagnostic accuracy, ability to evaluate functional capacity, and lack of radiation use associated with exercise stress echocardiography (ESE) render this method a first-line procedure for patients with suspected or confirmed coronary heart disease. The evaluation of Doppler data and the enormous amount of information obtained during and after exercise, including in a standing position if appropriate, in patients with hypertrophic cardiomyopathy, athletes, syndrome X patients and patients with valve and congenital heart disease necessitates the use of ESE.